Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

GALT

  • Official Full Name

    galactose-1-phosphate uridylyltransferase

  • Overview

    Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined.
  • Synonyms

    GALT; galactose-1-phosphate uridylyltransferase; gal-1-P uridylyltransferase; galactose-1-phosphate uridyl transferase; UDP-glucose--hexose-1-phosphate uridylyltransferase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Native Proteins
  • Bacillus subtilis
  • Human
  • Mouse
  • Rat
  • Yeast
  • Zebrafish
  • E. coli or Yeast
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • SUMO
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GALT-13147H Recombinant Human GALT, His-tagged E.coli His 1-379a.a.
Human GALT-7122H Recombinant Human GALT, His-tagged E.coli His 1-379aa
Human GALT-27306TH Recombinant Human GALT, His-tagged E.coli His
Human GALT-6026HCL Recombinant Human GALT 293 Cell Lysate HEK293 N/A
Human GALT-4714H Recombinant Human GALT Protein, GST-tagged Wheat Germ GST
Human GALT-2582H Recombinant Human GALT Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GALT-2938H Recombinant Human GALT protein, His-SUMO-tagged E.coli His-SUMO 1-379aa
Human GALT-5374HF Recombinant Full Length Human GALT Protein, GST-tagged In Vitro Cell Free System GST 379 amino acids
Mouse Galt-3146M Recombinant Mouse Galt Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat GALT-2474R Recombinant Rat GALT Protein Mammalian Cell His
Rat Galt-1613R Recombinant Rat Galt protein, His & T7-tagged E.coli His/T7 Met1~Ala379 (Accession # P43424)
Rat GALT-2130R Recombinant Rat GALT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GALT-2130R-B Recombinant Rat GALT Protein Pre-coupled Magnetic Beads HEK293
Bacillus subtilis GALT-0846B Recombinant Bacillus subtilis GALT protein, His-tagged E. coli or Yeast His
Yeast GALT-10 Active Native Streptoverticillium mobaraense Yeast
Zebrafish GALT-5107Z Recombinant Zebrafish GALT Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GALT Related Articles

GALT involved in several pathways and played different roles in them. We selected most pathways GALT participated on our site, such as Galactose metabolism, Amino sugar and nucleotide sugar metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GALT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Galactose metabolismG6PC;PFKL;AKR1B8;SI;GANC;AKR1B1L;LCT;G6PCA.1;HK1
Amino sugar and nucleotide sugar metabolismGNPDA1;CYB5R4;CYB5RL;HK3;TSTA3;GNPNAT1;FUK;GALT;GNE
Metabolic pathwaysDGAT1A;MTR;B3GNT5;NT5C;GFPT2;HSD3B4;CBR1;POLR3B;CHPT1
Prolactin signaling pathwayMAPK9;INS1;ESR1;SOCS7;NFKB1;PIK3R2;SHC4;STAT3;SOCS6

GALT has several biochemical functions, for example, UDP-glucose:hexose-1-phosphate uridylyltransferase activity, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GALT itself. We selected most functions GALT had, and list some proteins which have the same functions with GALT. You can find most of the proteins on our site.

Function Related Protein
UDP-glucose:hexose-1-phosphate uridylyltransferase activity
protein bindingSKIV2L2;H2-KE2;ASAP1;ASAP3;PLOD3;C1QB;NHLH2;CTSH;EIF4EBP1
zinc ion bindingNR4A2A;LMO2;RNF43;TRIM30A;PHF15;ATXN7L3;SORD;RARGB;ADAMTS16

GALT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GALT here. Most of them are supplied by our site. Hope this information will be useful for your research of GALT.

TNK2; TRIP13

Coelho, AI; Lourenco, S; et al. Functional correction by antisense therapy of a splicing mutation in the GALT gene. EUROPEAN JOURNAL OF HUMAN GENETICS 23:500-506(2015).
Viggiano, E; Marabotti, A; et al. Clinical and molecular spectra in galactosemic patients from neonatal screening in northeastern Italy: Structural and functional characterization of new variations in the galactose-1-phosphate uridyltransferase (GALT) gene. GENE 559:112-118(2015).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
How is GALT protein deficiency treated? 02/14/2023

Treatment for GALT deficiency involves a strict lactose-free diet, which means avoiding milk, dairy products, and other foods containing galactose.

Are there any specific dietary recommendations for individuals with GALT deficiency? 11/22/2021

Individuals with GALT deficiency are recommended to avoid galactose-containing foods, and dietary supplementation with essential nutrients may be necessary.

Can GALT deficiency lead to long-term complications? 02/13/2019

Yes, if left untreated, GALT deficiency can lead to long-term complications such as liver damage, cognitive impairment, and reproductive issues.

Can GALT protein levels be measured in the blood? 07/05/2017

Yes, GALT enzyme activity levels can be measured in the blood to diagnose GALT deficiency.

What are the symptoms of galactosemia? 02/27/2017

Symptoms of galactosemia include jaundice, poor feeding, vomiting, liver enlargement, and failure to thrive in infants. In older children and adults, symptoms may include cognitive impairment, speech difficulties, and ovarian insufficiency in females.

Customer Reviews (3)

Write a review
Reviews
12/19/2022

    The GALT Protein is an exceptional product that fully meets my experimental needs.

    02/10/2022

      Its versatility and reliability make it a top choice for researchers in various fields.

      10/20/2016

        The GALT Protein's adaptability has significantly expanded the scope of my investigations and broadened the possibilities for my research.

        Ask a Question for All GALT Products

        Required fields are marked with *

        My Review for All GALT Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends