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GART

  • Official Full Name

    phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

  • Overview

    The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
  • Synonyms

    GART; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; PGFT, PRGS; trifunctional purine biosynthetic protein adenosine-3; AIRS; GARS; PAIS; PGFT; PRGS; GARTF; MGC47764;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GART-26H Recombinant Human GART Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human GART-687HCL Recombinant Human GART cell lysate N/A
Human GART-4732H Recombinant Human GART Protein, GST-tagged Wheat Germ GST
Human GART-4265H Recombinant Human GART protein, His-tagged E.coli His 111–318aa
Human GART-5447HF Recombinant Full Length Human GART Protein, GST-tagged In Vitro Cell Free System GST 433 amino acids
Mouse GART-6212M Recombinant Mouse GART Protein Mammalian Cell His
Mouse Gart-3155M Recombinant Mouse Gart Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse GART-3471M Recombinant Mouse GART Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GART-3471M-B Recombinant Mouse GART Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GART-9156Z Recombinant Zebrafish GART Mammalian Cell His
Chicken GART-1112C Recombinant Chicken GART Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GART involved in several pathways and played different roles in them. We selected most pathways GART participated on our site, such as Purine metabolism, One carbon pool by folate, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GART were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismPDE3B;PDE7B;AK7;NUDT2;PNPT1;NUDT5;PKMA;POLR2F;AK2
One carbon pool by folateMTHFD1B;AMT;MTHFD2L;MTHFD1L;MTR;MTHFD2;DHFRL1;ATIC;ST20-MTHFS
Metabolic pathwaysGALK1;GUSB;AOC3;HK2;FBP1A;GLULC;PDXP;PTGDS;ACOT8

GART has several biochemical functions, for example, ATP binding, metal ion binding, methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GART itself. We selected most functions GART had, and list some proteins which have the same functions with GART. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMAP2K2;EPHA7;MATK;STK19;BMPR1AA;SMOK2B;CDC42BPB;CDC6;DARS2
metal ion bindingZDHHC14;ZSCAN10;DGKZ;ZNF524;ATP9B;VEPH1;FTR54;ACY3.1;KLF10
methyltransferase activityPRDM1;PRDM14;METTL6;TRMT10B;ALDH1L1;METTL25;SETD9;PCMT;MLL5
phosphoribosylamine-glycine ligase activity
phosphoribosylformylglycinamidine cyclo-ligase activity
phosphoribosylglycinamide formyltransferase activity

GART has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GART here. Most of them are supplied by our site. Hope this information will be useful for your research of GART.

ARF6; IKBKG; PXN; KPNA2; acuC; 15-deoxy-delta(12,14; FN1; VCAM1; Bmpr1a; NES; PPIA; VP35; NCBP1; DBN1; ATL3; Myh9; Bag2; MYO19

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