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GATAD2B

Official Full Name

GATA zinc finger domain containing 2B
Overview

Transcriptional repressor p66-beta is a protein that in humans is encoded by the GATAD2B gene.
Synonyms

GATAD2B; GATA zinc finger domain containing 2B; transcriptional repressor p66-beta; P66beta; transcription repressor p66 beta component of the MeCP1 complex; p66/p68; GATA zinc finger domain-containing protein 2B; FLJ37346; KIAA1150; RP11-216N14.6; MGC138;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GATAD2B-6007HCL	Recombinant Human GATAD2B 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GATAD2B-2643H	Recombinant Human GATAD2B protein, His-tagged	E.coli	His	1-170 aa	$319 / 25ug
Human	GATAD2B-4758H	Recombinant Human GATAD2B Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GATAD2B-5476HF	Recombinant Full Length Human GATAD2B Protein, GST-tagged	In Vitro Cell Free System	GST	593 amino acids	Inquiry
Mouse	GATAD2B-6230M	Recombinant Mouse GATAD2B Protein	Mammalian Cell	His		Inquiry
Mouse	GATAD2B-3487M	Recombinant Mouse GATAD2B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	GATAD2B-3487M-B	Recombinant Mouse GATAD2B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	GATAD2B-4063Z	Recombinant Zebrafish GATAD2B	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

GATAD2B involved in several pathways and played different roles in them. We selected most pathways GATAD2B participated on our site, such as Chromatin modifying enzymes, Chromatin organization, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with GATAD2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Chromatin modifying enzymes	ARID5B;CHD4;PHF8;SAP30L;MSL2A;BRPF3;USP22;SMARCB1;EED
Chromatin organization	C17orf81;DPY30;RUVBL2;PHF2;GATAD2B;MSL2A;ING3;COPRS;KDM3A
Gene Expression	TXN;NR2F6A;SUPT4H1;DNMT3A;RARG;ZNF34;ZNF75A;FAM36A;APOBEC1
HDACs deacetylate histones	SAP30;ANO9A;MBD3A;PHF21A;SAP30L;CHD4A;KDM1A;HMG20B;ARID4A
RNA Polymerase I Promoter Clearance	CD3EAP;MBD3A;RRN3;TAF1D;TAF1A;MBD3;TAF1B;CHD4;EHMT2
RNA Polymerase I Transcription	TAF1C;GATAD2A;EFCAB11;TAF1B;CD3EAP;MBD3A;PTRF;MBD3;MTA3
RNA Polymerase I Transcription Initiation	CHD4A;MBD3A;GATAD2AB;GATAD2A;CHD4;MTA1;MBD3B;MTA2;MBD3
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription	SNAPC1B;MBD3B;RRN3;NFIB;POLRMT;PTRFB;POU2F1;CBX3;BRF2

GATAD2B has several biochemical functions, for example, contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding, contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding, contributes_to nucleosomal DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GATAD2B itself. We selected most functions GATAD2B had, and list some proteins which have the same functions with GATAD2B. You can find most of the proteins on our site.

Function	Related Protein
contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding	HDAC2;GATAD2B;SMARCC1;CHD4;SMARCE1;MTA2;RBBP4;SMARCA4;SMARCC2
contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding	SMARCC2;SMARCA4;RBBP4;SMARCC1;GATAD2B;ACTL6A;MTA2;HDAC1;SMARCB1
contributes_to nucleosomal DNA binding	MBD3;CHD4;SMARCC2;SMARCA4;ACTB;ACTL6A;GATAD2B;HDAC2;SMARCB1
protein binding	RASL10B;KRT25;CCDC155;TCTN2;TRIM13;UNG;JAK3;DNAJB5;COL17A1
transcription factor activity, sequence-specific DNA binding	PCGF6;MYCLB;ZNF205;ZIC3;FOXP1B;POU3F2B;FOXJ1;EGR2B;ZFP583
zinc ion binding	FBXO11A;Shh;ESRRA;TRIM45;DNAJC24;ADAM17;RNF123;RXRG;TCEA2

GATAD2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GATAD2B here. Most of them are supplied by our site. Hope this information will be useful for your research of GATAD2B.

MBD3; HDAC1; PRKAB2; TRIM27; GOLGA2; TRAF1; CALCOCO2