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gB

  • Official Full Name

    genderblind

  • Overview

    Human cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B is a 907-amino acid glycoprotein encoded by the ORF of UL55. It is the most abundant component of the envelope with at least two defined neutralizing epitopes, a target of neutralizing antibodies and an essential replication component. The synthesized gB precursor matures into a 130-160 kDa glycoprotein by acquiring N-linked glycosylation modifications, and is cleaved by the cellular protease furin into two components, a 93-116 kDa N-terminal fragment and a 55 kDa C-terminal fragment linked by a disulfide-bond, which is presented on the viral envelope as well as on the surface of virus-infected cells as a covalently associated homodimer. gB plays important roles in HCMV entry, cell-cell spread of internal virions, and fusion of infected cells. It triggers penetration of cells and enhances the spread of infection in nonpolarized human fibroblasts.
  • Synonyms

    Glycoprotein B;

  • Recombinant Proteins
  • Transfected Stable Cell Lines
  • Antibody
  • Cell & Tissue Lysates
  • CMV
  • CyCMV
  • Cytomegalovirus
  • Epstein-Barr virus
  • HCMV
  • HCMV (strain AD169)
  • HCMV (strain Merlin)
  • HHV-2
  • HHV-5 (strain Towne)
  • HHV-6 variant A(strain Uganda-1102)
  • HHV-7
  • HSV-1
  • HSV-2
  • Human
  • Human herpes simplex virus 1
  • Human herpesvirus 1
  • Human herpesvirus 5
  • Human herpesvirus 7
  • Human herpesvirus 7 (strain JI) (HHV-7) (Human T lymphotropic virus)
  • PRV
  • Rhesus cytomegalovirus (strain 68-1)
  • Saimiriine herpesvirus 2 (strain 11) (SaHV-2) (Herpesvirus saimiri)
  • VZV
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • In vitro E. coli expression system
  • Insect Cell
  • Mouse
  • Rabbit
  • C
  • Fc
  • GST
  • hFc
  • His
  • Myc
  • His|GST
  • SUMO
  • human|IgG1|Fc
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human gB-112C Active Recombinant Human cytomegalovirus gB E.coli N/A
Human GB-8H Human haemoglobin Reference Standard N/A
Human CAB-699MH Mouse Anti-Human gB Monoclonal Antibody Mouse N/A
Human CAB-652RH Rabbit Anti-Human gB Monoclonal Antibody Rabbit N/A
CMV gB-1045C Recombinant Human cytomegalovirus (HCMV) gB protein(Met1-Lys700 & Arg777-Val907), Fc-tagged HEK293 C-Fc Met1-Lys700 & Arg777-Val907
CMV gB-109C Recombinant CMV gB protein, hFc-tagged HEK293 hFc Met1-Lys700
CMV gB-111C Recombinant CMV gB, His & GST tagged Human Cell His/GST
CMV gB-352V Recombinant CMV gB Protein, GST-tagged E.coli GST
CMV gB-110C Recombinant CMV gB, His tagged Human Cell His
CMV GB-2601CCL Recombinant CMV GB cell lysate Human Cell N/A
CMV gB-0297C Recombinant CMV gB protein HEK293 N/A Met1-Lys700 & Arg777-Val907
CyCMV GB-763V Recombinant CyCMV GB Protein, Fc-tagged HEK293 Fc
Cytomegalovirus gB-1033V Recombinant Cytomegalovirus gB Protein E.coli GST
Epstein-Barr virus gB-4104E Recombinant Epstein-Barr virus gB protein, His-SUMO-tagged E.coli His-SUMO 23-260aa
HCMV GB-18H Recombinant HCMV Glycoprotein B (GB) protein, Fc-tagged HEK293 human/IgG1/Fc 678
HCMV gB-1493H Recombinant HCMV gB protein, Fc-tagged HEK293 Fc Val23-Lys700
HCMV GB-355H Recombinant HCMV Glycoprotein B (GB) protein, Fc-tagged HEK293 human/IgG1/Fc 678
HCMV GB-356H Recombinant HCMV GB protein, His-tagged HEK293 His 809
HCMV (strain AD169) gB-1492H Active Recombinant HCMV (strain AD169) gB protein, His-tagged HEK293 His Ser25-Phe706
HCMV (strain Merlin) gB-1491H Active Recombinant HCMV (strain Merlin) gB protein, His-tagged HEK293 His Ser25-Glu698
HHV-2 gB-1999H Recombinant HHV-2 gB Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 23-904aa
HHV-5 (strain Towne) gB-761H Recombinant Human HHV-5 (strain Towne) gB Protein, Fc-tagged HEK293 Fc 907
HHV-6 variant A(strain Uganda-1102) gB-4266H Recombinant HHV-6 variant A(strain Uganda-1102) gB protein, His&Myc-tagged E.coli His&Myc 23-188aa
HHV-7 gB-2426H Recombinant HHV-7 gB Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 23-822aa
HSV-1 gB-501V Recombinant HSV-1 gB Protein E.coli N/A
HSV-1 gB-502V Recombinant HSV-1 gB Protein, His & Myc-tagged E.coli His/Myc 31-284aa
HSV-2 gB-457V Recombinant HSV-2 gB Protein E.coli N/A
HSV-2 gB-458V Recombinant HSV-2 gB Protein, His-SUMO-tagged E.coli His-SUMO 23-279aa
Human herpes simplex virus 1 gB-1307H Recombinant Human herpes simplex virus 1 gB protein, His&Myc-tagged HEK293 His&Myc 31-774aa
Human herpesvirus 1 gB-1261H Recombinant Human herpesvirus 1 gB protein, His&Myc-tagged Insect Cell His&Myc 31-774aa
Human herpesvirus 5 gB-5966H Recombinant Human herpesvirus 5 gB protein, His&Myc-tagged E.coli His&Myc 552-635aa
Human herpesvirus 7 gB-4055H Recombinant Human herpesvirus 7 gB protein, His-tagged E.coli His 23-259aa
Human herpesvirus 7 (strain JI) (HHV-7) (Human T lymphotropic virus) RFL2317HF Recombinant Full Length Human Herpesvirus 7 Envelope Glycoprotein B(Gb) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (23-822aa)
PRV gB-520V Recombinant PRV gB Protein E.coli N/A
Rhesus cytomegalovirus (strain 68-1) gB-3800R Recombinant Rhesus cytomegalovirus (strain 68-1) gB protein, His&Myc-tagged E.coli His&Myc 745-854aa
Saimiriine herpesvirus 2 (strain 11) (SaHV-2) (Herpesvirus saimiri) RFL14248SF Recombinant Full Length Saimiriine Herpesvirus 2 Envelope Glycoprotein B(Gb) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (20-808)
VZV gB-1698V Recombinant VZV gB Protein HEK293 N/A
  • gB Related Gene Family

gB involved in several pathways and played different roles in them. We selected most pathways gB participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with gB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

gB has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by gB itself. We selected most functions gB had, and list some proteins which have the same functions with gB. You can find most of the proteins on our site.

Function Related Protein

gB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with gB here. Most of them are supplied by our site. Hope this information will be useful for your research of gB.

IL
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