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GBP1

  • Official Full Name

    guanylate binding protein 1, interferon-inducible

  • Overview

    Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.
  • Synonyms

    GBP1; guanylate binding protein 1, interferon-inducible; guanylate binding protein 1, interferon inducible, 67kDa; interferon-induced guanylate-binding protein 1; GBP-1; huGBP-1; GTP-binding protein 1; guanine nucleotide-binding protein 1; guanylate bindi;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Pig
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GBP1-28991TH Recombinant Human GBP1 Wheat Germ N/A 592 amino acids
Human GBP1-13180H Recombinant Human GBP1, GST-tagged E.coli GST 242-592a.a.
Human GBP1-6940H Recombinant Human GBP1, His tagged Human Cell His
Human GBP1-53H Recombinant Human GBP1 protein, His-tagged E.coli His 607aa
Human GBP1-1686HCL Recombinant Human GBP1 cell lysate Human Cell N/A
Human GBP1-1324H Recombinant Human GBP1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human GBP1-182HF Recombinant Full Length Human GBP1 Protein In Vitro Cell Free System 592 amino acids
Human GBP1-5526H Recombinant Human GBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GBP1-4776H Recombinant Human GBP1 Protein, GST-tagged Wheat Germ GST
Human GBP1-2023HFL Recombinant Full Length Human GBP1 Protein, C-Flag-tagged Mammalian cells Flag
Human GBP1-13181H Recombinant Human GBP1 protein, His-tagged E. coli His 242-592 aa
Human GBP1-5522HF Recombinant Full Length Human GBP1 Protein, GST-tagged In Vitro Cell Free System GST 592 amino acids
Human GBP1-968H Recombinant Human GBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GBP1-968H-B Recombinant Human GBP1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GBP1-492Z Recombinant Zebrafish GBP1 Mammalian Cell His
Pig GBP1-945P Recombinant Pig GBP1 Protein, His-tagged E.coli N-His Lys35-Lys275
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GBP1 Related Gene Family

GBP1 involved in several pathways and played different roles in them. We selected most pathways GBP1 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine Signaling in Immune systemEDARADD;IFI30;KPNA4;SPTB;NEFLB;CRK;UBE2V1;IFI6;USP18
Immune SystemTREML4;SIGLEC9;KIR2DS2;STUB1;TRIM45;CD160;MYO9B;CLEC2D;IgG3
Interferon SignalingTRIM10;HERC5;IRF2;TRIM31;FCGR1B;TRIM2;IFIT2;IRF4;MX2
Interferon gamma signalingTRIM38;TRIM3;GBP6;TRIM31;TRIM45;GBP4;TRIM29;TRIM10;TRIM2
Type II interferon signaling (IFNG)Ifna;REG1A;GBP1;IFI6;IFIT2

GBP1 has several biochemical functions, for example, GTP binding, GTPase activity, Hsp90 protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GBP1 itself. We selected most functions GBP1 had, and list some proteins which have the same functions with GBP1. You can find most of the proteins on our site.

Function Related Protein
GTP bindingIRGF1;RAB40B;SAR1AB;RTKN;URGCP;ARL4D;RAB3C;GNL3L;RAB9B
GTPase activityEEF1A1A;RNF112;RABL2A;RALBA;RAB12;EEFSEC;RAB21;DNM3A;TUBA4A
Hsp90 protein bindingPACRG;RPS3;PPID;NASP;FKBP6;GBP1;ARNTL;EIF2AK3;PPEF2
actin bindingMYH7;WDR1;LRRK2;AKAP5;DMD;EZRA;MYOZ2;PIP;RUSC1
cytokine bindingNRP2;ELANE;Fzd4;IFNGR1;IL17F;CXCR4;TNFRSF11A;CSF1R;CNTFR
enzyme bindingGSTM7;RPS19BP1;A2M;PAWR;SELS;GNB2L1;POR;CDK19;HDAC6
identical protein bindingSID4;TRADD;PRPF19;LRP6;STAT2;NCAM1;AGXT2;KIRRELA;HSPB1
protein bindingPEX5;CBLL1;GPR37L1;RTN1;SCAMP1;PRPF4B;ASCC1;COBL;TAF7L
spectrin bindingADD1;PDE6G;MYO10;GNB1;CAMSAP1L1;KIF3A;DYNC1I1;STX4A;UNC13A

GBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GBP1.

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