GCA
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Official Full Name
grancalcin, EF-hand calcium binding protein
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Overview
This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. -
Synonyms
GCA; grancalcin, EF-hand calcium binding protein; grancalcin, EF hand calcium binding protein; grancalcin; GCL; OTTHUMP00000162937; OTTHUMP00000204639; grancalcin, penta-EF-hand protein; grancalcin, EF-hand calcium-binding protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Human
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- GCA Related Articles
- GCA Related Research Area
GCA involved in several pathways and played different roles in them. We selected most pathways GCA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GCA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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GCA has several biochemical functions, for example, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GCA itself. We selected most functions GCA had, and list some proteins which have the same functions with GCA. You can find most of the proteins on our site.
Function | Related Protein |
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calcium ion binding | ANXA1;PLCZ1;CALM1;LDLRB;EHD3;FSTL1A;PCDHGB6;SYT16;PCDH2G3 |
calcium-dependent cysteine-type endopeptidase activity | CAPN1;CAPN5;CAPN2B;PDCD6;CAPN2L;CAPNS1;CAPN3;CAPN3A;CAPN3B |
protein binding | FAM114A1;HSPD1;TNIK;C14orf118;LNX2B;NADK;YTHDF3;EVC2;TTC1 |
protein heterodimerization activity | CHRNB2;ANO9A;ZFP423;MYH7;SDCBP2;H2AFB3;SOX8;BMP7A;IKZF2 |
protein homodimerization activity | PTS;BAXB;CDSN;GRIK1;PRDX4;FAP;TG;NRF1;TFAP4 |
GCA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GCA here. Most of them are supplied by our site. Hope this information will be useful for your research of GCA.
MAGEA8; EIF3H; ATXN1; EBNA2; RBFOX1
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Ask a questionCustomer Reviews (3)
Write a reviewIn ELISA assays, it has consistently exhibited exceptional reliability and accuracy, providing precise and reproducible results.
Their prompt and knowledgeable guidance has been instrumental in effectively addressing my queries and optimizing the utilization of the GCA protein in my studies.
The GCA protein comes highly recommended for its outstanding performance in various experimental applications.
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