gdnf
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  • Official Full Name
  • glial cell derived neurotrophic factor
  • Background
  • This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010]
  • Synonyms
  • GDNF; glial cell derived neurotrophic factor; ATF1; ATF2; HSCR3; HFB1-GDNF; glial cell line-derived neurotrophic factor; ATF; astrocyte-derived trophic factor;
Cat.#:GDNF-4835HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GDNF Protein, GST-tagged
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Cat.#:GDNF-637HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GDNF Protein
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Cat.#:GDNF-708HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human GDNF Protein
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Cat.#:Gdnf-359RTag:N/A
Source (Host):Sf 21 Insect cellsSpecies:Rat
Product nameRecombinant Rat Glial Cell Derived Neurotrophic Factor
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Cat.#:GDNF-03HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Glial Cell Derived Neurotrophic Factor
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Cat.#:GDNF-15HTag:His/S
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GDNF Protein, His/S-tagged
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Cat.#:GDNF-22HTag:His
Source (Host):Barley grain (Hordeum vulgare)Species:Human
Product nameRecombinant Human GDNF, His-tagged
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Cat.#:GDNF-26274THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GDNF
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Cat.#:GDNF-28231THTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GDNF
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Cat.#:GDNF-338HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Glial Cell Derived Neurotrophic Factor
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Cat.#:GDNF-535HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GDNF
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Cat.#:GDNF-7292HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human GDNF, None tagged
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Cat.#:GDNF-7293HTag:Fc/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human GDNF protein, Fc/His-tagged
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Cat.#:GDNF-778HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GDNF protein, His-tagged
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Cat.#:GDNF-8858HTag:
Source (Host):Hordeum vulgareSpecies:Human
Product nameRecombinant Human GDNF,His-tagged
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Cat.#:GDNF-985HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human GDNF
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Cat.#:Gdnf-16MTag:His/S
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse GDNF Protein, His/S-tagged
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Cat.#:Gdnf-249MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gdnf
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Cat.#:GDNF-6293MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GDNF Protein
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Cat.#:Gdnf-779MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gdnf protein, His-tagged
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Cat.#:Gdnf-250RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Glial Cell Derived Neurotrophic Factor
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Cat.#:Gdnf-595RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gdnf
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Cat.#:Gdnf-7431RTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Rat
Product nameRecombinant Rat Gdnf, His tagged
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Cat.#:Gdnf-780RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gdnf protein, His-tagged
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Cat.#:GDNF-1066CTag:Fc
Source (Host):HEK293Species:Canine
Product nameRecombinant Canine GDNF Protein, Fc-tagged
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Cat.#:GDNF-3352HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GDNF
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Cat.#:GDNF-1549HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human GDNF cell lysate
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Cat.#:GDNF-400RCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Rat
Product nameRecombinant Rat GDNF cell lysate
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Cat.#:GDNF-133HGTag:
Source (Host):NS0Species:Human
Product nameGMP Recombinant Human GDNF Protein
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Cat.#:GDNF-34HTag:
Source (Host):Species:Human
Product nameHuman Glial cell line-derived neurotrophic factor Reference standard
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GDNF Related Articles

Battaglia, G; Riozzi, B; et al. Activation of mGlu3 metabotropic glutamate receptors enhances GDNF and GLT-1 formation in the spinal cord and rescues motor neurons in the SOD-1 mouse model of amyotrophic lateral sclerosis. NEUROBIOLOGY OF DISEASE 74:126-136(2015).
Lajoie, JM; Shusta, EV; et al. Targeting Receptor-Mediated Transport for Delivery of Biologics Across the Blood-Brain Barrier. ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 55 55:613-631(2015).