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GEMIN6

  • Official Full Name

    gem (nuclear organelle) associated protein 6

  • Overview

    The survival of motor neurons (SMN) complex is essential for the biogenesis of small nuclear ribonucleoprotein (snRNP) complexes in eukaryotic cells. Reduced levels of SMN cause the motor neuron degenerative disease, spinal muscular atrophy. Complexes containing Gemin3-Gemin4-Gemin5 and Gemin6-Gemin7-unrip persist at similar levels when SMN is reduced. Gemin5-containing subunits bind small nuclear RNA independently of the SMN complex and without a requirement for exogenous ATP. ATP hydrolysis is, however, required for displacement of small nuclear RNAs from the Gemin5-containing subunits and their assembly into snRNPs.
  • Synonyms

    GEMIN6; gem (nuclear organelle) associated protein 6; gem-associated protein 6; FLJ23459; SIP2; gemin 6; gemin-6;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Strep
  • Myc
  • DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GEMIN6-13224H Recombinant Human GEMIN6, GST-tagged E.coli GST 1-167a.a.
Human GEMIN6-7560H Recombinant Human GEMIN6, His-tagged E.coli His 1-167aa
Human GEMIN6-5960HCL Recombinant Human GEMIN6 293 Cell Lysate HEK293 N/A
Human GEMIN6-1260H Recombinant Human GEMIN6 Protein (M1-Q167), Tag Free E.coli No tag M1-Q167
Human GEMIN6-1261H Recombinant Human GEMIN6 Protein (M1-Q167), His/Strep tagged E.coli His/Strep M1-Q167
Human GEMIN6-5311HF Recombinant Full Length Human GEMIN6 Protein, GST-tagged In Vitro Cell Free System GST 167 amino acids
Human GEMIN6-4842H Recombinant Human GEMIN6 Protein, GST-tagged Wheat Germ GST
Mouse GEMIN6-6302M Recombinant Mouse GEMIN6 Protein Mammalian Cell His
Mouse Gemin6-3189M Recombinant Mouse Gemin6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse GEMIN6-3530M Recombinant Mouse GEMIN6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GEMIN6-3530M-B Recombinant Mouse GEMIN6 Protein Pre-coupled Magnetic Beads HEK293
Chicken GEMIN6-5094C Recombinant Chicken GEMIN6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GEMIN6 involved in several pathways and played different roles in them. We selected most pathways GEMIN6 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with GEMIN6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA transportSUMO3B;UPF3B;EIF3H;CLNS1A;EIF1AY;NUP160;EIF2B1;EIF2B2;SIP1

GEMIN6 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GEMIN6 itself. We selected most functions GEMIN6 had, and list some proteins which have the same functions with GEMIN6. You can find most of the proteins on our site.

Function Related Protein
protein bindingEEF2;RND2;ZNF335;KXD1;RRAGA;SLC25A46;HOMER2;TARDBP;NHP2

GEMIN6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GEMIN6 here. Most of them are supplied by our site. Hope this information will be useful for your research of GEMIN6.

GEMIN7; STRAP; TOX4; vpr; JAK3; GPSM2; Smn1; SMN1

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