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GFER

  • Official Full Name

    growth factor, augmenter of liver regeneration

  • Overview

    The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008]
  • Synonyms

    GFER; growth factor, augmenter of liver regeneration; ALR; HPO; HSS; ERV1; HPO1; HPO2; HERV1; FAD-linked sulfhydryl oxidase ALR; ERV1 homolog; hepatopoietin protein; erv1-like growth factor; hepatic regenerative stimulation substance;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • His|T7
  • Myc
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GFER-27232TH Recombinant Human GFER Wheat Germ N/A 125 amino acids
Human GFER-7080H Recombinant Human GFER, His-tagged E.coli His 1-205aa
Human GFER-662H Recombinant Human GFER Protein, His-tagged HEK293 His
Human GFER-216H Recombinant Human GFER, His-SUMO-tagged HEK293 His/SUMO
Human GFER-205H Recombinant Human GFER, His-SUMO-tagged, C13&N15 Labeled HEK293 His/SUMO
Human GFER-5954HCL Recombinant Human GFER 293 Cell Lysate HEK293 N/A
Human GFER-1412H Recombinant Human GFER Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GFER-5317HF Recombinant Full Length Human GFER Protein, GST-tagged In Vitro Cell Free System GST 125 amino acids
Human GFER-4849H Recombinant Human GFER Protein, GST-tagged Wheat Germ GST
Human GFER-491H Recombinant Human GFER Protein 205
Human GFER-190HF Recombinant Full Length Human GFER Protein In Vitro Cell Free System 125 amino acids
Human GFER-3342H Recombinant Human GFER protein(Met1-Asp125), His-tagged E. coli N-His Met1-Asp125
Mouse GFER-6308M Recombinant Mouse GFER Protein Mammalian Cell His
Mouse Gfer-587M Recombinant Mouse Gfer Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse GFER-3536M-B Recombinant Mouse GFER Protein Pre-coupled Magnetic Beads HEK293
Mouse GFER-3536M Recombinant Mouse GFER Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Gfer-1609M Recombinant Mouse Gfer protein, His & T7-tagged E.coli His/T7 Gly13~Asp198 (Accession # P56213)
Rat GFER-1225R Recombinant Rat GFER Protein, His-SUMO-tagged E.coli His/SUMO
Rat GFER-2509R Recombinant Rat GFER Protein Mammalian Cell His
Rat GFER-2165R Recombinant Rat GFER Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GFER-2165R-B Recombinant Rat GFER Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GFER-5532Z Recombinant Zebrafish GFER Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GFER involved in several pathways and played different roles in them. We selected most pathways GFER participated on our site, such as Metabolism of proteins, Mitochondrial protein import, which may be useful for your reference. Also, other proteins which involved in the same pathway with GFER were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metabolism of proteinsSAMM50;DNAJC19;EEF1A1;IGFBP2A;ST6GALNAC1.2;ST6GAL2B;ATP6AP2;TBCD;IGFBP5B
Mitochondrial protein importTIMM13;TOMM22;CHCHD4;BCS1L;TIMM21;TIMM22;PMPCB;GFER;TIMM17B

GFER has several biochemical functions, for example, flavin adenine dinucleotide binding, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GFER itself. We selected most functions GFER had, and list some proteins which have the same functions with GFER. You can find most of the proteins on our site.

Function Related Protein
flavin adenine dinucleotide bindingNOS1;AIFM3;NOX4;KDM1B;ACOX2;AOX3L1;IVD;NOX5;ETFDH
growth factor activityFGF20A;INHA;NDR2;AMH;INHBAB;LIF;VEGFC;BMP10;GMFB
protein bindingWBP1;HDAC3;KRT86;PIBF1;SPRED1;FKBPL;FOXM1;TESK2;PTRH2
protein disulfide oxidoreductase activityGLRX5;DNAJC10;CCS;SH3BGRL3;GLRX2;PTGES2;TXN;TXNRD1;PTGESL
thiol oxidase activityGFER;TMX3

GFER has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GFER here. Most of them are supplied by our site. Hope this information will be useful for your research of GFER.

COPS2; GPS1; COPS5; COPS8; PLEKHF2

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