Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

GGT6

Official Full Name

gamma-glutamyltransferase 6
Overview

GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular;enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl;moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione;synthesis (Heisterkamp et al., 2008 (PubMed 18357469)).
Synonyms

GGT6; gamma-glutamyltransferase 6; gamma glutamyltransferase 6 homolog (rat); FLJ90165; Gamma glutamyltranspeptidase 6; GGT 6; gamma-glutamyltranspeptidase 6; gamma-glutamyltransferase 6 homolog;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GGT6-701HCL	Recombinant Human GGT6 cell lysate		N/A		Inquiry
Human	GGT6-4878H	Recombinant Human GGT6 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GGT6-5242HF	Recombinant Full Length Human GGT6 Protein, GST-tagged	In Vitro Cell Free System	GST	493 amino acids	Inquiry
Mouse	GGT6-6333M	Recombinant Mouse GGT6 Protein	Mammalian Cell	His		Inquiry
Mouse	GGT6-3545M	Recombinant Mouse GGT6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	GGT6-3545M-B	Recombinant Mouse GGT6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GGT6-2524R	Recombinant Rat GGT6 Protein	Mammalian Cell	His		Inquiry
Rat	GGT6-2180R-B	Recombinant Rat GGT6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GGT6-2180R	Recombinant Rat GGT6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein

GGT6 involved in several pathways and played different roles in them. We selected most pathways GGT6 participated on our site, such as Aflatoxin activation and detoxification, Biological oxidations, Cyanoamino acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGT6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Aflatoxin activation and detoxification	PRKRA;CYP2A13;CYP3A5;CYP2Y3;ACY3.2;ACY3;FAM84B;DPEP1;CYP3C1
Biological oxidations	CYP2A7;CYP24A1;CYP3A7-CYP3AP1;PAOX;UGT1B2;ADH7;CYP2R1;CYP2C18;ACY3.2
Cyanoamino acid metabolism	SHMT2;SHMT1;GGT1A;GGT7;GGT6;GGT1;GGT5A;GGT5;GBA3
Glutathione conjugation	GSTO2;GSTK1;GGT6;GGTLC1;AKR1A1
Glutathione metabolism	GSTM1;SRM;GPX5;GSTA4;GSTM4;IDH1;GSTA3;G6PD;GGT7
Glutathione synthesis and recycling	GGTLC1;GGT6
Metabolic pathways	MT-ATP6;CYP24A1;NAT;HAO1;SPHK1;GAMT;EPHX2;GMPPA;MAN1A2
Metabolism	CYP3A7-CYP3AP1;ATP5S;NAALAD2;FAAH2A;KIAA1199;CDS1;SLC25A15A;INSIG1;SLC27A2A

GGT6 has several biochemical functions, for example, gamma-glutamyltransferase activity, glutathione hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GGT6 itself. We selected most functions GGT6 had, and list some proteins which have the same functions with GGT6. You can find most of the proteins on our site.

Function	Related Protein
gamma-glutamyltransferase activity	GGT5;GGTLC1;GGT1;GGT6;GGT1A;GGT7;GGT5A
glutathione hydrolase activity	GGT7;GGT6;GGT1;GGT5

GGT6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GGT6 here. Most of them are supplied by our site. Hope this information will be useful for your research of GGT6.

hpaE