GLMN
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Official Full Name
glomulin, FKBP associated protein
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Overview
This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. -
Synonyms
GLMN; glomulin, FKBP associated protein; venous malformation with glomus cells , VMGLOM; glomulin; FAP48; FKBPAP; GLML; GVM; FAP; FK506 binding protein associated protein; FKBP associated protein; VMGLOM; OTTHUMP00000011939; OTTHUMP00000011940; FKBP-associated protein; FK506-binding protein-associated protein; FAP68;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | GLMN-5900HCL | Recombinant Human GLMN 293 Cell Lysate | HEK293 | N/A |
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| Human | GLMN-5335HF | Recombinant Full Length Human GLMN Protein, GST-tagged | In Vitro Cell Free System | GST | 594 amino acids |
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| Human | GLMN-4965H | Recombinant Human GLMN Protein, GST-tagged | Wheat Germ | GST |
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| Human | GLMN-5740H | Recombinant Human GLMN Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Mouse | Glmn-1291M | Recombinant Mouse Glmn protein, His & T7-tagged | E.coli | His/T7 | Val294~Pro549 (Accession # Q8BZM1) |
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| Mouse | GLMN-6411M | Recombinant Mouse GLMN Protein | Mammalian Cell | His |
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| Mouse | GLMN-3598M-B | Recombinant Mouse GLMN Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | Glmn-3226M | Recombinant Mouse Glmn Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Mouse | GLMN-3598M | Recombinant Mouse GLMN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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- Involved Pathway
- Protein Function
- Interacting Protein
GLMN involved in several pathways and played different roles in them. We selected most pathways GLMN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GLMN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
GLMN has several biochemical functions, for example, hepatocyte growth factor receptor binding, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GLMN itself. We selected most functions GLMN had, and list some proteins which have the same functions with GLMN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hepatocyte growth factor receptor binding | GLMN;ESM1 |
| protein binding | KLC4;EFTUD2;NUB1;TEF;Ccl27a;HIST1H4B;MAP4K5;NDUFAF1;PRKCI |
| ubiquitin protein ligase binding | RANGAP1;TMEM189;SLC25A5;SPOP;AXIN1;FAF2;CASP10;MOAP1;CUL4B |
| ubiquitin-protein transferase inhibitor activity | GLMN;CDKN2A |
GLMN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLMN here. Most of them are supplied by our site. Hope this information will be useful for your research of GLMN.
HSPB1; NSFL1C; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; FKBP4; FKBP5; CDC37; CDC37L1; TMEM173; SAV1
- Q&As
- Reviews
Q&As (5)
Ask a questionStudies have suggested that GLMN protein levels may influence the response of cancer cells to chemotherapy, potentially affecting treatment outcomes.
GLMN protein levels may have diagnostic applications in identifying abnormal mTORC1 signaling in certain diseases, providing insights into disease mechanisms and potential treatment strategies.
Genetic mutations in the GLMN gene have been associated with certain diseases, including cardiomyopathy and skeletal muscle disorders.
The expression of GLMN protein is regulated by various factors, including transcriptional regulation and post-translational modifications.
Genetic variations in the GLMN gene may impact protein expression and function, potentially contributing to disease susceptibility and progression.
Customer Reviews (3)
Write a reviewIts purity and consistency are of the highest standards, allowing for precise and reliable results in my research endeavors.
The GLMN Protein is a protein of exceptional quality that surpasses my expectations and fulfills all my experimental requirements.
The manufacturer's commitment to excellence is truly commendable, especially when it comes to their outstanding technical support.
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