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GLUD2

  • Official Full Name

    Glud2 glutamate dehydrogenase 2

  • Synonyms

    GLUD2; glutamate dehydrogenase 2; Glud-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • E.coli
  • HEK293T
  • In Vitro Cell Free System
  • Wheat Germ
  • GST
  • His
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GLUD2-13320H Recombinant Human GLUD2, GST-tagged E.coli GST 207-558a.a.
Human GLUD2-27654TH Recombinant Human GLUD2, His-tagged E.coli His
Human GLUD2-90H Recombinant Human GLUD2, GST-tagged Wheat Germ GST
Human GLUD2-89H Recombinant Human GLUD2, GST-tagged Wheat Germ GST
Human GLUD2-716HCL Recombinant Human GLUD2 cell lysate N/A
Human GLUD2-6941HF Recombinant Full Length Human GLUD2 Protein, GST-tagged In Vitro Cell Free System GST 558 amino acids
Human GLUD2-444H Recombinant Human GLUD2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GLUD2-6940HF Recombinant Full Length Human GLUD2 Protein, GST-tagged In Vitro Cell Free System GST 558 amino acids
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GLUD2 Related Articles
  • GLUD2 Related Research Area

GLUD2 involved in several pathways and played different roles in them. We selected most pathways GLUD2 participated on our site, such as Arginine biosynthesis, Alanine, aspartate and glutamate metabolism, D-Glutamine and D-glutamate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLUD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Arginine biosynthesisARG1;NOS3;NOS2B;GLUD1B;GOT2;ASS1;GLUD1;GLUL;NOS1
Alanine, aspartate and glutamate metabolismGLUD1;AGXTA;GPT2L;ABAT;GLUD1A;ASL2;GOT2B;GLUD1B;GAD1B
D-Glutamine and D-glutamate metabolismGLUD1B;GLUD1;GLUD2;ybaS;GLSA;GLS2;GLS;GLUD1A
Nitrogen metabolismCA14;CAR7;CA12;CA9;CA4;CA8;CA4A;CA7;CA5A
Metabolic pathwaysFASN;PAICS;CYP2C19;BCO1;RPN1;TUSC3;NMRK2;PAFAH1B1A;UGT1A7C
Carbon metabolismMCEE;PC;FH1;CAT;SHMT2;DLAT;ACO2;GPR19;PSPH
Proximal tubule bicarbonate reclamationCar4;ATP1A3;ATP1A2;CA2;PCK2;GLUD1;MDH1;SLC25A10;AQP1

GLUD2 has several biochemical functions, for example, ADP binding, GTP binding, glutamate dehydrogenase (NAD+) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GLUD2 itself. We selected most functions GLUD2 had, and list some proteins which have the same functions with GLUD2. You can find most of the proteins on our site.

Function Related Protein
ADP bindingMYH10;LONP1;GCLC;PKM;PRPS2;MYO7A;VCP;P2RY1;HSP104
GTP bindingRAB40C;SEPT8B;RAB24;GIMAP5;RAB14;IIGP1;IRGF4;TUBA1L;NUDT2
glutamate dehydrogenase (NAD+) activityGLUD2;GLUD1
glutamate dehydrogenase [NAD(P)+] activityGLUD1;GLUD2
leucine bindingGLUD1;GLUD2;UBR1;UBR2

GLUD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLUD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GLUD2.

MYC; TRMT10C; TOM1L1; ATF2; CLPP

Bhandage, AK; Jin, Z; et al. GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics. FRONTIERS IN CELLULAR NEUROSCIENCE 8:-(2014).
Botman, D; Tigchelaar, W; et al. Determination of Phosphate-activated Glutaminase Activity and Its Kinetics in Mouse Tissues using Metabolic Mapping (Quantitative Enzyme Histochemistry). JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 62:813-826(2014).
  • Q&As
  • Reviews

Q&As (7)

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What is the impact of altered GLUD2 activity on metabolic disorders? 04/06/2023

Altered GLUD2 activity can impact brain metabolism and contribute to metabolic and neurological disorders.

How do genetic variations in GLUD2 affect its enzymatic activity? 08/30/2020

Genetic mutations in GLUD2 can affect its function, potentially leading to neurological imbalances.

How does GLUD2 contribute to the regulation of neurotransmitter levels? 06/09/2019

It helps regulate neurotransmitter levels by converting glutamate to α-ketoglutarate.

What potential therapeutic applications arise from targeting GLUD2 in neurological conditions? 01/10/2019

Targeting GLUD2 could provide new treatments for conditions related to neurotransmitter imbalances.

What role does GLUD2 play in brain function and neurologic health? 10/04/2018

GLUD2 is important for brain function, influencing neurotransmitter balance and neuronal activity.

How does GLUD2 interact with other metabolic pathways in the brain? 03/26/2018

GLUD2 interacts with energy metabolism pathways in the brain, affecting neuronal energy supply.

What is the primary role of GLUD2 in amino acid metabolism? 03/29/2017

GLUD2, a glutamate dehydrogenase, is key in metabolizing glutamate, an important amino acid in the brain.

Customer Reviews (3)

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Reviews
09/15/2022

    Consistency in quality. Supports our research consistently.

    10/07/2020

      Precision in analysis. Vital for our research goals.

      11/24/2018

        Expert service quality. Aids our research significantly.

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