GLYAT
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Official Full Name
glycine-N-acyltransferase
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Overview
The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is;thought to be important in the detoxification of endogenous and xenobiotic acyl-CoAs. Two transcript variants;encoding different isoforms have been found for this gene. -
Synonyms
GLYAT; glycine-N-acyltransferase; glycine N-acyltransferase; ACGNAT; GAT; AAc; HRP-1(CLP); aralkyl-CoA N-acyltransferase; acyl-CoA:glycine N-acyltransferase; aralkyl acyl-CoA N-acyltransferase; aralkyl acyl-CoA:amino acid N-acyltransferase; CAT;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- GLYAT Related Articles
GLYAT involved in several pathways and played different roles in them. We selected most pathways GLYAT participated on our site, such as Amino Acid conjugation, Amino acid conjugation of benzoic acid, Biological oxidations, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLYAT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Amino Acid conjugation | GLYATL2;GLYAT;GLYATL1;ACSM1 |
| Amino acid conjugation of benzoic acid | GLYAT;GLYATL1;GLYATL2 |
| Biological oxidations | CYP2B6;SLC35B3;UGT1B1;TPMT.2;SULT1ST6;ADH6;CYP24A1;CYP2C8;DPEP2 |
| Conjugation of benzoate with glycine | ACSM1;GLYAT;GLYATL1;GLYATL2 |
| Conjugation of carboxylic acids | GLYAT;GLYATL1;ACSM1;GLYATL2 |
| Conjugation of salicylate with glycine | GLYATL1;GLYAT;GLYATL2 |
| Metabolism | COX4I1;SLC25A15B;DUT;MED29;TIAM2;OAZ3;UGT1B2;CYP2W1;COX14 |
| Phase II conjugation | GLYATL2;SULT1B1;UGT1B3;UGT1B2;GLYATL1;GGTLC1;UGT1B5;SULT4A1;ABHD14B |
GLYAT has several biochemical functions, for example, glycine N-acyltransferase activity, glycine N-benzoyltransferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GLYAT itself. We selected most functions GLYAT had, and list some proteins which have the same functions with GLYAT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glycine N-acyltransferase activity | KEG1;GLYATL1;GLYAT;GLYATL2;GM4952 |
| glycine N-benzoyltransferase activity | |
| protein binding | NUDT12;SH3PXD2A;ARGLU1;MC5R;CFH;NQO1;ZNF302;HDGFRP2;CCT2 |
| transferase activity, transferring acyl groups | ZDHHC15B;LPGAT1;CHAC2;TMEM68;Nat3;ZDHHC6;AANAT;ZDHHC14;NAT15 |
GLYAT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLYAT here. Most of them are supplied by our site. Hope this information will be useful for your research of GLYAT.
KRTAP10-8; NOTCH2NL; PA; PTN; RBM48; VOPP1
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