gm2a
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  • Official Full Name
  • GM2 ganglioside activator
  • Background
  • This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
  • Synonyms
  • GM2A; GM2 ganglioside activator; GM2 ganglioside activator protein; ganglioside GM2 activator; cerebroside sulfate activator protein; SAP 3; sphingolipid activator protein 3; Ganglioside GM2 activator isoform short; Ganglioside GM2 activator precursor; GM2 AP; GM2-AP; GM2AP; OTTHUMP00000160619; SAP-3; SAP3; SAP3_HUMAN; Shingolipid activator protein 3
Cat.#:GM2A-5001HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GM2A Protein, GST-tagged
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Cat.#:GM2A-27454THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human GM2A
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Cat.#:GM2A-27456THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human GM2A
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Cat.#:GM2A-521HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human GM2A Protein, His-tagged
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Cat.#:GM2A-556HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GM2A protein, His-tagged
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Cat.#:GM2A-554CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus GM2A Protein, His-tagged
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Cat.#:GM2A-2558ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GM2A
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Cat.#:GM2A-450HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human GM2A cell lysate
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GM2A Related Articles

Molnar, J; Nagy, T; et al. Genome sequencing and analysis of Mangalica, a fatty local pig of Hungary. BMC GENOMICS 15:-(2014).
Sinici, I; Yonekawa, S; et al. In Cellulo Examination of a Beta-Alpha Hybrid Construct of Beta-Hexosaminidase A Subunits, Reported to Interact with the GM2 Activator Protein and Hydrolyze GM2 Ganglioside. PLOS ONE 8:-(2013).