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GNPTG

  • Official Full Name

    N-acetylglucosamine-1-phosphate transferase, gamma subunit

  • Overview

    This gene encodes the gamma sunbunit of the N-acetylglucosamine-1-phosphotransferase complex. This hexameric complex, composed of alpha, beta and gamma subunits, catalyzes the first step in synthesis of a mannose 6-phosphate lysosomal recognition marker. This enzyme complex is necessary for targeting of lysosomal hydrolases to the lysosome. Mutations in the gene encoding the gamma subunit have been associated with mucolipidosis IIIC, also known as mucolipidosis III gamma.
  • Synonyms

    GNPTG; N-acetylglucosamine-1-phosphate transferase, gamma subunit; C16orf27, chromosome 16 open reading frame 27 , GNPTAG, N acetylglucosamine 1 phosphotransferase, gamma subunit; N-acetylglucosamine-1-phosphotransferase subunit gamma; c316G12.3; CAB56184; GlcNAc phosphotransferase gamma subunit; GlcNAc-1-phosphotransferase subunit gamma; GNPTAG; LP2537; N-acetylglucosamine-1-phosphate transferase gamma subunit; RJD9; UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma; C16orf27;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GNPTG-13379H Recombinant Human GNPTG, His-tagged E.coli His 5-304a.a.
Human GNPTG-5840HCL Recombinant Human GNPTG 293 Cell Lysate HEK293 N/A
Human GNPTG-5095H Recombinant Human GNPTG Protein, GST-tagged Wheat Germ GST
Human GNPTG-5406HF Recombinant Full Length Human GNPTG Protein, GST-tagged In Vitro Cell Free System GST 19-304 amino acids
Human GNPTG-5153H Recombinant Human GNPTG Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse GNPTG-7054M Recombinant Mouse GNPTG Protein Mammalian Cell His
Mouse GNPTG-3786M-B Recombinant Mouse GNPTG Protein Pre-coupled Magnetic Beads HEK293
Mouse Gnptg-3266M Recombinant Mouse Gnptg Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse GNPTG-3786M Recombinant Mouse GNPTG Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish GNPTG-291Z Recombinant Zebrafish GNPTG Mammalian Cell His
Chicken GNPTG-4952C Recombinant Chicken GNPTG Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GNPTG Related Articles

GNPTG involved in several pathways and played different roles in them. We selected most pathways GNPTG participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNPTG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
LysosomeHGSNAT;MFSD8;AP3S1;GNSA;AP1S3B;LAMP2;ATP6V1H;AP3B2;NAGLU

GNPTG has several biochemical functions, for example, UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNPTG itself. We selected most functions GNPTG had, and list some proteins which have the same functions with GNPTG. You can find most of the proteins on our site.

Function Related Protein
UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activityGNPTAB;GNPTG
protein homodimerization activityAMBP;NR0B1;TCF3A;AGXT;SEPT12;GPD1;PITX2;HMOX1;AP1S2

GNPTG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNPTG here. Most of them are supplied by our site. Hope this information will be useful for your research of GNPTG.

SRPK1; phnI; kefB; UPF1; ANAPC15; Cdc23; Anapc2; Cdc16; Cdc26

Chen, H; Xu, JQ; et al. Association study of stuttering candidate genes GNPTAB, GNPTG and NAGPA with dyslexia in Chinese population. BMC GENETICS 16:-(2015).
Idol, RA; Wozniak, DF; et al. Neurologic Abnormalities in Mouse Models of the Lysosomal Storage Disorders Mucolipidosis II and Mucolipidosis III gamma. PLOS ONE 9:-(2014).
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