GOLGA2
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Official Full Name
golgin A2
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Overview
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010] -
Synonyms
GOLGA2; golgin A2; GM130; Golgin subfamily A member 2; golgin-95; SY11 protein; GM130 autoantigen; Golgi matrix protein GM130; 130 kDa cis-Golgi matrix protein; golgi autoantigen, golgin subfamily a, 2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Zebrafish
- E.coli
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | GOLGA2-29029TH | Recombinant Human GOLGA2, His-tagged | E.coli | His |
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| Human | GOLGA2-726HCL | Recombinant Human GOLGA2 cell lysate | N/A |
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| Human | GOLGA2-3291H | Recombinant Human GOLGA2 Protein (Ala361-Ala678), N-His tagged | E.coli | N-His | Ala361-Ala678 |
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| Human | GOLGA2-5105H | Recombinant Human GOLGA2 Protein, GST-tagged | Wheat Germ | GST |
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| Human | GOLGA2-5421HF | Recombinant Full Length Human GOLGA2 Protein, GST-tagged | In Vitro Cell Free System | GST | 345 amino acids |
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| Human | GOLGA2-01H | Recombinant Human GOLGA2 Protein, GST-tagged | Wheat Germ | GST |
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| Zebrafish | GOLGA2-6782Z | Recombinant Zebrafish GOLGA2 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
GOLGA2 involved in several pathways and played different roles in them. We selected most pathways GOLGA2 participated on our site, such as Asparagine N-linked glycosylation, COPII (Coat Protein 2) Mediated Vesicle Transport, Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with GOLGA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Asparagine N-linked glycosylation | NEU3;NAPAB;SEC16B;CSNK1D;TMED2;MLEC;SERPINA1L;TRAPPC1;ST3GAL3A |
| COPII (Coat Protein 2) Mediated Vesicle Transport | GORASP1;PPP6C;CSNK1D;NSFA;NAPB;CTSZ;SEC23IP;NAPAA;TRAPPC9 |
| Cell Cycle | ANAPC4;TRP53;SDCCAG8;CDC7;CDC14B;CNEP1R1;ANAPC7;HAUS2;UBE2V2 |
| Cell Cycle, Mitotic | NEK9;ZWILCH;CSNK2A2;ZWINT;LIN9;CENPQ;DPF1;DCTN1A;CENPK |
| ER to Golgi Anterograde Transport | PPP6R3;NAPAA;MIA3;TRAPPC3;CTSC;CTSZ;SERPINA1L;TRAPPC6BL;NAPAB |
| Golgi Cisternae Pericentriolar Stack Reorganization | GOLGA2;BLZF1;GORASP1;USO1;GORASP2 |
| M Phase | SMC2;SGOL2;NSL1;SPC24;ARPP19B;ENSA;SPDL1;NEK7;GORASP1 |
| Membrane Trafficking | GORASP1;TPD52;SNX9A;RAB10;TCEAL4;GJC1;NSFA;STAM2;TERFA |
GOLGA2 has several biochemical functions, for example, importin-alpha family protein binding, microtubule binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GOLGA2 itself. We selected most functions GOLGA2 had, and list some proteins which have the same functions with GOLGA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| importin-alpha family protein binding | GOLGA2;TPX2;RAN |
| microtubule binding | KIF5B;KIF20A;KIF2A;APC2;KIF3C;CLIP3;CAMSAP1;GABARAPA;KIF16B |
| protein binding | WNT3;DYNLL2;KPNA4;CHN1;CNTNAP2;SSB;HSD17B8;MRPS16;CTLA4 |
| protein kinase binding | PLCG1;GDF3;DUSP3;CDK5RAP2;TRAF6;BAG5;VRK2;NBEA;KCNQ3 |
| syntaxin binding | CPLX3;SYT9;CPLX2;SYT11B;SYTL2;CPLX4A;PTPN2;TMED10;NAPB |
GOLGA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GOLGA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GOLGA2.
STK25; CCNH; TRIM29; DCX
- Q&As
- Reviews
Q&As (5)
Ask a questionGOLGA2 protein is involved in regulating vesicular transport and protein trafficking within the cell, contributing to cellular signaling pathways.
Monitoring GOLGA2 protein levels may provide insights into disease progression and treatment response in certain clinical conditions.
Some genetic mutations in the GOLGA2 gene have been linked to developmental disorders and neurodevelopmental conditions.
The expression and activity of GOLGA2 protein are regulated by various cellular mechanisms, including post-translational modifications and protein-protein interactions.
GOLGA2 protein has been implicated in drug resistance mechanisms, and its overexpression may contribute to resistance to certain anticancer drugs.
Customer Reviews (3)
Write a reviewIts remarkable purity and functional attributes make it an optimal choice for my research, ensuring accurate and reliable outcomes.
The manufacturer's prompt and reliable technical support serves as an invaluable resource, reinforcing my confidence in the GOLGA2 protein's effectiveness and enabling smooth progress in my experiments.
I am eager to embark on this scientific journey, empowered by the high-quality GOLGA2 protein and the manufacturer's unparalleled assistance.
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