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GPR119

  • Official Full Name

    G protein-coupled receptor 119

  • Synonyms

    GPR119; G protein-coupled receptor 119; glucose-dependent insulinotropic receptor; GPCR2; hGPCR2; G-protein coupled receptor 2; G-protein coupled receptor 119; MGC119957;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GPR119-5800HCL Recombinant Human GPR119 293 Cell Lysate HEK293 N/A
Human GPR119-5177H Recombinant Human GPR119 Protein, GST-tagged Wheat Germ GST
Human GPR119-5176H Recombinant Human GPR119 Protein Wheat Germ N/A
Human GPR119-5609HF Recombinant Full Length Human GPR119 Protein In Vitro Cell Free System 1,079 amino acids
Mouse GPR119-7132M Recombinant Mouse GPR119 Protein Mammalian Cell His
Mouse GPR119-3842M Recombinant Mouse GPR119 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GPR119-3842M-B Recombinant Mouse GPR119 Protein Pre-coupled Magnetic Beads HEK293
Rat GPR119-2648R Recombinant Rat GPR119 Protein Mammalian Cell His
Rat GPR119-2302R Recombinant Rat GPR119 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GPR119-2302R-B Recombinant Rat GPR119 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL25888HF Recombinant Full Length Human Glucose-Dependent Insulinotropic Receptor(Gpr119) Protein, His-Tagged E.coli expression system His Full Length (1-335)
Mus musculus (Mouse) RFL1588MF Recombinant Full Length Mouse Glucose-Dependent Insulinotropic Receptor(Gpr119) Protein, His-Tagged E.coli expression system His Full Length (1-335)
Rattus norvegicus (Rat) RFL10488RF Recombinant Full Length Rat Glucose-Dependent Insulinotropic Receptor(Gpr119) Protein, His-Tagged E.coli expression system His Full Length (1-468)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GPR119 Related Articles

GPR119 involved in several pathways and played different roles in them. We selected most pathways GPR119 participated on our site, such as Incretin synthesis, secretion, and inactivation, Insulin secretion, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR119 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Incretin synthesis, secretion, and inactivationPCSK1;CDX2;GPR120;SPCS3;GPR119;SLC38A8;GRP;O3far1;DPP4
Insulin secretionATP1A4;PRKCA;PRKACB;PRKACG;CREB3L3;Adcy4;CREB3L1;PDX1;RYR2
Metabolism of proteinsTOMM22;SLC30A5;PFDN6;TOMM20;MUC12;TIMM17A;CXXC1;GPR119;APCS
Peptide hormone metabolismBCHE;CPA3;MBOAT4;DPP4;SLC30A8;PCSK1;SPCS3;RAB27A;CPN1
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)PCSK1;DPP4;GPR119
cAMP signaling pathwayF2R;PTGER2;CAMK2A;RRAS2;GRIA2;ACOX1;SOX9;GPR119;SUCNR1

GPR119 has several biochemical functions, for example, G-protein coupled receptor activity, phosphatidylcholine binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR119 itself. We selected most functions GPR119 had, and list some proteins which have the same functions with GPR119. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityOLFR13;GPR183A;GPR124;S1PR4;S1PR5A;MRGPRH;FZD7A;PARAPINOPSINB;OLFR151
phosphatidylcholine bindingNF1;VPS24;APOA4B.2;CETP;CHMP3;RPE65;APOA1A;RASGRP1;ALDOB

GPR119 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR119 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR119.

Cornall, LM; Hryciw, DH; et al. Direct activation of the proposed anti-diabetic receptor, GPR119 in cardiomyoblasts decreases markers of muscle metabolic activity. MOLECULAR AND CELLULAR ENDOCRINOLOGY 402:72-85(2015).
Engelstoft, MS; Norn, C; et al. Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119. BRITISH JOURNAL OF PHARMACOLOGY 171:5774-5789(2014).
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