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GPR120

  • Official Full Name

    O3FAR1 omega-3 fatty acid receptor 1

  • Overview

    This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein;functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory;responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this;gene.
  • Synonyms

    GT01; PGR4; GPR120; GPR129; MGC119984; DKFZp686F0824; omega-3 fatty acid receptor 1; OTTHUMP00000032309; OTTHUMP00000032310; G protein-coupled receptor 120; G protein-coupled receptor 129; G-protein coupled receptor 120; G-protein coupled receptor 129; G protein-coupled receptor PGR4; G-protein coupled receptor GT01; G-protein coupled receptor PGR4; G-protein-coupled receptor GT01;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GPR120-5799HCL Recombinant Human GPR120 293 Cell Lysate HEK293 N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GPR120 involved in several pathways and played different roles in them. We selected most pathways GPR120 participated on our site, such as Class A/1 (Rhodopsin-like receptors), Free fatty acid receptors, GPCR ligand binding, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR120 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Class A/1 (Rhodopsin-like receptors)CCRL2;DRD2;KISS1;EDN2;OPN1LW1;HCRT;CXCR7B;GPR18;PROK2
Free fatty acid receptorsGPR120;GPR31;GPR31B;FFAR3
GPCR ligand bindingEMR3;PTGDR2;CRHB;NMB;TAS2R7;GPRC6A;GPR65;TAAR1;TAS2R16
Incretin synthesis, secretion, and inactivationPCSK1;GPR119;GRP;SPCS3;GPR120;SLC38A8;O3far1;DPP4;CDX2
Metabolism of proteinsCPB1;MIA3;NAT8;IGFBP1A;TFG;DAD1;DDX11;MUC5AC;ADAMTS13
Peptide hormone metabolismPCSK2;SLC38A8;SLC30A8;CGB5;PCSK1;RAB27A;DPP4;INHA;O3far1
Signal TransductionCDC42EP1B;NPHP4;PYGO2;KEL;ARHGAP15;METAP2B;RGS10;RHOUA;TLE3
Signaling by GPCRPTHLHA;OBSCN;ZFPM2B;GPR55;ARHGAP4;TAS2R13;UTS2;RAMP3;MLN

GPR120 has several biochemical functions, for example, fatty acid binding, NOT peptide binding, taste receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR120 itself. We selected most functions GPR120 had, and list some proteins which have the same functions with GPR120. You can find most of the proteins on our site.

Function Related Protein
fatty acid bindingGPR120;FABP1;FABP7B;FABP4;FABP1B.1;FABP10A;APOC1;Alb;ADH5
NOT peptide binding
taste receptor activityO3far1;TAS2R134;TAS2R137;TAS2R108;TAS2R7;TAS2R140;TAS2R139;TAS2R143;TAS1R2

GPR120 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR120 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR120.

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