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GPRC5B

Official Full Name

G protein-coupled receptor, family C, group 5, member B
Overview

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade.
Synonyms

GPRC5B; G protein-coupled receptor, family C, group 5, member B; G protein coupled receptor, family C, group 1, member B; G-protein coupled receptor family C group 5 member B; RAIG 2; A-69G12.1; retinoic acid-induced gene 2 protein; retinoic acid responsi;

Type

Cell & Tissue Lysates
Recombinant Proteins

Species

Homo sapiens (Human)
Human
Mus musculus (Mouse)

Source

E.coli
E.coli expression system
HEK293
In Vitro Cell Free System
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GPRC5B-5770HCL	Recombinant Human GPRC5B 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GPRC5B-1846H	Recombinant Human GPRC5B protein, GST-tagged	E.coli	GST	293-331 aa	$319 / 25ug
Human	GPRC5B-5285H	Recombinant Human GPRC5B Protein	Wheat Germ	N/A		Inquiry
Human	GPRC5B-5286H	Recombinant Human GPRC5B Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GPRC5B-5544HF	Recombinant Full Length Human GPRC5B Protein, GST-tagged	In Vitro Cell Free System	GST	29-403 amino acids	Inquiry
Human	GPRC5B-5538HF	Recombinant Full Length Human GPRC5B Protein	In Vitro Cell Free System		473 amino acids	Inquiry
Homo sapiens (Human)	RFL406HF	Recombinant Full Length Human G-Protein Coupled Receptor Family C Group 5 Member B(Gprc5B) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (29-403)	Inquiry
Mus musculus (Mouse)	RFL33569MF	Recombinant Full Length Mouse G-Protein Coupled Receptor Family C Group 5 Member B(Gprc5B) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (29-410)	Inquiry

Involved Pathway
Protein Function
Interacting Protein
GPRC5B Related Articles

GPRC5B involved in several pathways and played different roles in them. We selected most pathways GPRC5B participated on our site, such as GPCRs, Class C Metabotropic glutamate, pheromone, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPRC5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
GPCRs, Class C Metabotropic glutamate, pheromone	GPRC5C;CASR;GPRC5A;GPRC5B;GPRC5D

GPRC5B has several biochemical functions, for example, G-protein coupled receptor activity, G-protein coupled receptor binding, protein kinase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPRC5B itself. We selected most functions GPRC5B had, and list some proteins which have the same functions with GPRC5B. You can find most of the proteins on our site.

Function	Related Protein
G-protein coupled receptor activity	GPR62;Fzd4;TAS2R125;FZD1;TAAR7F;OXGR1A.3;GPR81;TAS2R201.1;FZD3
G-protein coupled receptor binding	FYN;UCN3L;RSPO1;FCN1;PROK2;HSPA1A;GNA11B;GNAT2;GNAL
protein kinase activator activity	NCKAP1L;NKX3-1;DBF4B;FAM58A;PRKAG2;MAPK8IP2;TOM1L1;STK11;WNT11
protein kinase binding	CCNT2B;C10orf46;DNAJA3;TRAF4;FAM83D;CNTLN;CDK5RAP1;PRKACA;PTPN2

GPRC5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPRC5B here. Most of them are supplied by our site. Hope this information will be useful for your research of GPRC5B.

C11orf71

Hippe, HJ; Freundt, G; et al. Orphan receptor GPRC5b activates inflammatory signaling in vascular smooth muscle cells. EUROPEAN HEART JOURNAL 35:1024-1024(2014).

Hinney, A; Albayrak, O; et al. Genetic Variation at the CELF1 (CUGBP, Elav-Like Family Member 1 Gene) Locus is Genome-Wide Associated With Alzheimer's Disease and Obesity. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 165:283-293(2014).