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GPX6

Official Full Name

glutathione peroxidase 6 (olfactory)
Overview

This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3 UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Expression of this gene is restricted to embryos and adult olfactory epithelium.
Synonyms

GPX6; glutathione peroxidase 6 (olfactory); glutathione peroxidase pseudogene 3 , GPXP3;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
His|T7

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Mouse	GPX6-7234M	Recombinant Mouse GPX6 Protein	Mammalian Cell	His		Inquiry
Mouse	Gpx6-1108M	Recombinant Mouse Gpx6 protein, His & T7-tagged	E.coli	His/T7	Gln20~Gln221 (Accession # Q91WR8)	Inquiry
Mouse	GPX6-3905M	Recombinant Mouse GPX6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	GPX6-3905M-B	Recombinant Mouse GPX6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GPX6-2681R	Recombinant Rat GPX6 Protein	Mammalian Cell	His		Inquiry
Rat	Gpx6-1109R	Recombinant Rat Gpx6 protein, His & T7-tagged	E.coli	His/T7	Gln20~Gln221 (Accession # Q64625)	Inquiry
Rat	GPX6-2335R	Recombinant Rat GPX6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	GPX6-2335R-B	Recombinant Rat GPX6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
GPX6 Related Articles

GPX6 involved in several pathways and played different roles in them. We selected most pathways GPX6 participated on our site, such as Glutathione metabolism, Arachidonic acid metabolism, Thyroid hormone synthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPX6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glutathione metabolism	GGCTA;GPX7;GSTA3;GPX3;MGST3;GGT5;GSS;RRM2B;MGST1.1
Arachidonic acid metabolism	CYP2P8;FAAH2A;FAAH2;CBR1L;GPX2;PLA2G1B;PLA2G4C;CYP2C45;PLA2G6
Thyroid hormone synthesis	CREB5;GPX6;HSPA5;PRKCA;ATP1B3;GPX5;TPO;SLC26A4;ITPR1

GPX6 has several biochemical functions, for example, glutathione peroxidase activity, oxidoreductase activity, peroxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPX6 itself. We selected most functions GPX6 had, and list some proteins which have the same functions with GPX6. You can find most of the proteins on our site.

Function	Related Protein
glutathione peroxidase activity	GSTT1;GPX6;LTC4S;GPX2;GSTZ1;CLIC2;MGST1;GPX8;GRX2
oxidoreductase activity	CYP4F14;CYP2AA3;DAO.1;LEPREL1;ACOXL;HEPHL1;SDR16C5B;CYP11C1;AOC1
peroxidase activity	PTGS2A;PRDX1;PTGS2B;MPX;GPX1A;GPX7;GPX1B;GPX8;CYGB

GPX6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPX6 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPX6.

Leonard, B; Maes, M; et al. Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS 36:764-785(2012).

Hashimoto, K; Ueda, S; et al. Neuroprotective effects of melatonin on the nigrostriatal dopamine system in the zitter rat. NEUROSCIENCE LETTERS 506:79-83(2012).