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GRIK5

Official Full Name

glutamate receptor, ionotropic, kainate 5
Overview

glutamate receptor subunit KA2; associates with subunits of the GluR5-7 family to form heteromeric kainate-preferring glutamate receptpors
Synonyms

GRIK5; glutamate receptor, ionotropic, kainate 5; glutamate receptor, ionotropic kainate 5; KA2; glutamate receptor KA2; glutamate receptor KA-2; iGlu5;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GRIK5-5646HF	Recombinant Full Length Human GRIK5 Protein	In Vitro Cell Free System		168 amino acids	Inquiry
Human	GRIK5-5341H	Recombinant Human GRIK5 Protein	Wheat Germ	N/A		Inquiry
Mouse	GRIK5-7268M	Recombinant Mouse GRIK5 Protein	Mammalian Cell	His		Inquiry
Mouse	GRIK5-3930M	Recombinant Mouse GRIK5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	GRIK5-3930M-B	Recombinant Mouse GRIK5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GRIK5-2699R	Recombinant Rat GRIK5 Protein	Mammalian Cell	His		Inquiry
Rat	GRIK5-2353R-B	Recombinant Rat GRIK5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GRIK5-2353R	Recombinant Rat GRIK5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	GRIK5-8075Z	Recombinant Zebrafish GRIK5	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
GRIK5 Related Articles

GRIK5 involved in several pathways and played different roles in them. We selected most pathways GRIK5 participated on our site, such as Neuroactive ligand-receptor interaction, Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIK5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Neuroactive ligand-receptor interaction	PRLR;S1PR4;HTR2CL1;NPY2R;PTGER1B;GABRR3A;TRY;TAAR14L;OPRD1A
Glutamatergic synapse	GRIN3A;SLC38A3;Adcy4;SHANK2;GNAI1;MAPK1;GRIK1;TRPC1;SLC38A2

GRIK5 has several biochemical functions, for example, PDZ domain binding, SH3 domain binding, extracellular-glutamate-gated ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIK5 itself. We selected most functions GRIK5 had, and list some proteins which have the same functions with GRIK5. You can find most of the proteins on our site.

Function	Related Protein
PDZ domain binding	GRID2;PDZK1;CADM1;SLC22A5;ATP2B3B;NSF;DTNA;LLGL2;LIN7C
SH3 domain binding	SH3BGR;DOCK4;VASPA;INPP5J;PTPN22;MAPT;KHDRBS1;CD3E;ADAM12
extracellular-glutamate-gated ion channel activity	GRIN2C;GRIA4A;GRIK5;GRIN2D;GRIK1;GRIN3A;GRIA1;GRIN1;GRIA2B
glutamate receptor activity	GRM4;GRID2;GRM7;GRM6;GRIK3;GRM2;GRIA1;GRIK5;GRM5
identical protein binding	ZBTB16;LDHB;FBXW7;BIN1;ESYT2;KHDC1A;ADIPOR1;BRAF;CEACAM5
ion channel activity	KCNA6A;FXYD5;GRIA3B;CHRNA4B;TRPC5A;GRIK3;TRPM1;KCNV2;TRPC2B
ionotropic glutamate receptor activity	GRIA2B;GRIA4;GRIK5;GRIA1A;GRIA4A;GRIA2A;GRIN2A;GRIA3B;GRIK3
kainate selective glutamate receptor activity	GRIK2;GRIK4;GRIK1;GRIK5;GRIK3
protein binding	COX5A;PLEKHN1;C9orf142;HIP1;SCARA3;QARS;GSTK1;TRIM16;ASXL1
receptor activity	VAC14;CD40;CMKLR1;CD200R3;XPR1;ADCYAP1R1;TLR1;LILRB3;CD160

GRIK5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIK5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIK5.

Dlg4

Takenouchi, T; Hashida, N; et al. 1p34.3 Deletion Involving GRIK3: Further Clinical Implication of GRIK Family Glutamate Receptors in the Pathogenesis of Developmental Delay. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164:456-460(2014).

Sanchez-Martin, FJ; Fan, YX; et al. Lead Induces Similar Gene Expression Changes in Brains of Gestationally Exposed Adult Mice and in Neurons Differentiated from Mouse Embryonic Stem Cells. PLOS ONE 8:-(2013).