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GRSF1

Official Full Name

G-rich RNA sequence binding factor 1
Overview

G-rich sequence factor 1 (GRSF-1) is a cytoplasmic protein that binds RNAs containing the G-rich element. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. GRSF-1 is up-regulated with prostate cancer progression and down regulated by the differentiating agents phenylacetate and phenylbutyrate. The function of GRSF-1 is uncharacterized, but potential roles include mRNA transport, stabilization, or translation. It might react with G-rich containing mRNA of Bcl2 and Bax indicating a regulation role of GRSF-1 in metastatic prostate cancer.
Synonyms

GRSF1; G-rich RNA sequence binding factor 1; G-rich sequence factor 1; GRSF-1; FLJ13125;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Rhesus Macaque
Zebrafish

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GRSF1-5384H	Recombinant Human GRSF1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GRSF1-5613HF	Recombinant Full Length Human GRSF1 Protein, GST-tagged	In Vitro Cell Free System	GST	459 amino acids	Inquiry
Rhesus Macaque	GRSF1-1982R	Recombinant Rhesus monkey GRSF1 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	GRSF1-1803R	Recombinant Rhesus Macaque GRSF1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	GRSF1-1803R-B	Recombinant Rhesus Macaque GRSF1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	GRSF1-4430Z	Recombinant Zebrafish GRSF1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
GRSF1 Related Articles

GRSF1 involved in several pathways and played different roles in them. We selected most pathways GRSF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GRSF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

GRSF1 has several biochemical functions, for example, nucleic acid binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRSF1 itself. We selected most functions GRSF1 had, and list some proteins which have the same functions with GRSF1. You can find most of the proteins on our site.

Function	Related Protein
nucleic acid binding	VEZF1B;DNAJC21;ZFP541;ZFP110;HIVEP2A;SRSF1B;BCL11BA;RECQL5;SPAG7
nucleotide binding	GSPT1L;EIF3BA;RBM12;PTBP1A;CPEB1A;FIGN;DNM2A;CKBA;MYH9A

GRSF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRSF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRSF1.

Piekna-Przybylska, D; Sullivan, MA; et al. U3 Region in the HIV-1 Genome Adopts a G-Quadruplex Structure in Its RNA and DNA Sequence. BIOCHEMISTRY 53:2581-2593(2014).

BIRNBAUM, MJ; WRIGHT, KL; et al. FUNCTIONAL-ROLE FOR SP1 IN THE TRANSCRIPTIONAL AMPLIFICATION OF A CELL-CYCLE-REGULATED HISTONE H4 GENE. BIOCHEMISTRY 34:7648-7658(1995).