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GSC

  • Official Full Name

    goosecoid homeobox

  • Overview

    This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis.
  • Synonyms

    GSC; goosecoid homeobox; homeobox protein goosecoid;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GSC-13555H Recombinant Human GSC, His-tagged E.coli His 1-257a.a.
Human GSC-5728HCL Recombinant Human GSC 293 Cell Lysate HEK293 N/A
Human GSC-5617HF Recombinant Full Length Human GSC Protein, GST-tagged In Vitro Cell Free System GST 257 amino acids
Human GSC-5387H Recombinant Human GSC Protein, GST-tagged Wheat Germ GST
Mouse GSC-7302M Recombinant Mouse GSC Protein Mammalian Cell His
Mouse GSC-3950M Recombinant Mouse GSC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GSC-3950M-B Recombinant Mouse GSC Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GSC-8647Z Recombinant Zebrafish GSC Mammalian Cell His
Chicken GSC-6883C Recombinant Chicken GSC Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GSC Related Articles

GSC involved in several pathways and played different roles in them. We selected most pathways GSC participated on our site, such as Regulation of nuclear SMAD2/3 signaling, Regulation of retinoblastoma protein, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Regulation of nuclear SMAD2/3 signalingSKI;CITED1;GSC;MYOD1;SNIP1;NKX2;CBFB;FOXH1
Regulation of retinoblastoma proteinBRD2;MYOD1;AATF;ATF7;BGLAP;CKM;CBX4;GSC;ELF1

GSC has several biochemical functions, for example, RNA polymerase II repressing transcription factor binding, RNA polymerase II transcription factor binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GSC itself. We selected most functions GSC had, and list some proteins which have the same functions with GSC. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II repressing transcription factor bindingCHD4;TBX5A;GSC;GTF2A2;MTA1;BBS7;PPARA;PROL1;BBS2
RNA polymerase II transcription factor bindingANKRD1;TBX20;MKX;TEAD3;TBX6;MIXL1;GSC;NFATC1;GATA6
sequence-specific DNA bindingNR4A2A;HOXA9B;TFAP4;IRX3A;RXRBA;CHES1;DLX5A;HOXC13A;HOXA4

GSC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSC here. Most of them are supplied by our site. Hope this information will be useful for your research of GSC.

Bayin, NS; Modrek, AS; et al. Selective Lentiviral Gene Delivery to CD133-Expressing Human Glioblastoma Stem Cells. PLOS ONE 9:-(2014).
Ivanov, VN; Hei, TK; et al. Radiation-induced glioblastoma signaling cascade regulates viability, apoptosis and differentiation of neural stem cells (NSC). APOPTOSIS 19:1736-1754(2014).
  • Q&As
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