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GSDMB

Official Full Name

gasdermin B
Overview

This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.
Synonyms

GSDMB; gasdermin B; gasdermin like , GSDML; gasdermin-B; PRO2521; 123; 156; Gasdermin like protein; Gasdermin-like protein; GSDMB_HUMAN; GSDML; PP4052; OTTHUMP00000164329; OTTHUMP00000164330; OTTHUMP00000164331; OTTHUMP00000164332; OTTHUMP00000227622;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian cells
Wheat Germ

Tag

Flag
GST
His (Fc)
Avi
His
Myc
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GSDMB-4391H	Recombinant Human GSDMB Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GSDMB-311HCL	Recombinant Human GSDMB Lysate	HEK293	N/A		Inquiry
Human	GSDMB-1028HFL	Recombinant Full Length Human GSDMB Protein, C-Flag-tagged	Mammalian cells	Flag		Inquiry
Human	GSDMB-1182H	Recombinant Human GSDMB protein, His&Myc-tagged	E.coli	His&Myc	1-411aa	Inquiry
Human	GSDMB-1024H	Recombinant Human GSDMB Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	GSDMB-2354H	Recombinant Human GSDMB Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	GSDMB-1024H-B	Recombinant Human GSDMB Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	GSDMB-3325HF	Recombinant Full Length Human GSDMB Protein, GST-tagged	In Vitro Cell Free System	GST	411 amino acids	Inquiry

Involved Pathway
Protein Function
Interacting Protein
GSDMB Related Articles

GSDMB involved in several pathways and played different roles in them. We selected most pathways GSDMB participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GSDMB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

GSDMB has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GSDMB itself. We selected most functions GSDMB had, and list some proteins which have the same functions with GSDMB. You can find most of the proteins on our site.

Function	Related Protein

GSDMB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSDMB here. Most of them are supplied by our site. Hope this information will be useful for your research of GSDMB.

SERPINA1; AGT; ORM1; HIVEP1; IGFBP2; PEBP1

Acevedo, N; Reinius, LE; et al. Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locus. HUMAN MOLECULAR GENETICS 24:875-890(2015).

van der Valk, RJP; Duijts, L; et al. Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 134:46-55(2014).