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GSTA5

Official Full Name

glutathione S-transferase alpha 5
Overview

The glutathione S-transferases (GST; EC 2.5.1.18) catalyze the conjugation of reduced glutathiones and a variety of electrophiles, including many known carcinogens and mutagens. The cytosolic GSTs belong to a large superfamily, with members located on different chromosomes. For additional information on GSTs, see GSTA1 (MIM 138359).
Synonyms

GSTA5; glutathione S-transferase alpha 5; glutathione S transferase A5; glutathione S-transferase A5; glutathione S transferase alpha 5; glutathione S transferase Yc 2; Glutathione S-transferase A5-5; GST A5 5; GST class-alpha member 5; GST Yc2; Gsta5 glutathione S transferase Yc2 subunit; GSTA5_HUMAN; glutathione transferase A5;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Cynomolgus Monkey
Human
Rat

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GSTA5-849H	Recombinant Human GSTA5	Mammalian Cell	His		Inquiry
Human	GSTA5-4412H	Recombinant Human GSTA5 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GSTA5-5716HCL	Recombinant Human GSTA5 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GSTA5-3343HF	Recombinant Full Length Human GSTA5 Protein, GST-tagged	In Vitro Cell Free System	GST	222 amino acids	Inquiry
Human	GSTA5-3087H	Recombinant Human GSTA5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	GSTA5-3087H-B	Recombinant Human GSTA5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	Gsta5-2014R	Recombinant Rat Gsta5 protein, His-tagged	E.coli	His	Met1~Ser221 (Accession # P46418)	Inquiry
Cynomolgus Monkey	GSTA5-573C	Recombinant Cynomolgus GSTA5 Protein, His-tagged	Mammalian Cell	His		Inquiry
Cynomolgus Monkey	GSTA5-319C	Recombinant Cynomolgus Monkey GSTA5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Cynomolgus Monkey	GSTA5-319C-B	Recombinant Cynomolgus Monkey GSTA5 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
GSTA5 Related Articles

GSTA5 involved in several pathways and played different roles in them. We selected most pathways GSTA5 participated on our site, such as Glutathione metabolism, Metabolism of xenobiotics by cytochrome P, Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glutathione metabolism	GSTM;GPX4A;GSTP1;GGT5;GSTT1B;GGCTA;GSTT1;TXNDC12;GSS
Metabolism of xenobiotics by cytochrome P	UGT5G1;UGT1A3;GSTM;GSTM5;CYP1A;GSTA3;GSTAL;GSTO1;UGT1A6A
Drug metabolism - cytochrome P	UGT2B15;GSTA4;UGT1A7;GSTT2B;GSTM1;AOX3;GSTM4;GSTT1;FMO3
Chemical carcinogenesis	UGT1A9;CYP2C39;NAT2;CYP3A7-CYP3AP1;ALDH3B1;GSTM3;SULT2A1;CYP2A6;UGT2B15

GSTA5 has several biochemical functions, for example, glutathione transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTA5 itself. We selected most functions GSTA5 had, and list some proteins which have the same functions with GSTA5. You can find most of the proteins on our site.

Function	Related Protein
glutathione transferase activity	GSTM;GSTM7;MGST3;GSTAL;GSTA2;GSTM2;GSTK1;GSTA3;GDAP1L1

GSTA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTA5.

Miao, WM; Hu, LG; et al. Oltipraz is a bifunctional inducer activating both phase I and phase II drug-metabolizing enzymes via the xenobiotic responsive element. MOLECULAR PHARMACOLOGY 64:346-354(2003).

Staffas, L; Ellis, EM; et al. Growth hormone- and testosterone-dependent regulation of glutathione transferase subunit A5 in rat liver. BIOCHEMICAL JOURNAL 332:763-768(1998).