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GSTZ1

  • Official Full Name

    glutathione transferase zeta 1

  • Overview

    This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.
  • Synonyms

    GSTZ1; glutathione transferase zeta 1; maleylacetoacetate isomerase; GSTZ1 1; MAAI; MAI; EC 2.5.1.18; EC 5.2.1.2; Glutathione S transferase zeta 1; GSTZ1-1; OTTHUMP00000246405; OTTHUMP00000246406; OTTHUMP00000246407; OTTHUMP00000246408; OTTHUMP00000246409; OTTHUMP00000246410; OTTHUMP00000246413; maleylacetone isomerase; glutathione S-aryltransferase; glutathione S-alkyltransferase; glutathi;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • MYC
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GSTZ1-909H Recombinant Human GSTZ1 Protein, His-tagged E.coli His
Human GSTZ1-13585H Recombinant Human GSTZ1, GST-tagged E.coli GST 1-216a.a.
Human GSTZ1-910H Recombinant Human GSTZ1 Protein, His-tagged E.coli His
Human GSTZ1-1947H Recombinant Human Glutathione transferase zeta 1, His-tagged E.coli His
Human GSTZ1-4432H Recombinant Human GSTZ1 Protein, GST-tagged Wheat Germ GST
Human GSTZ1-8644H Recombinant Human GSTZ1, His tagged E.coli N/A
Human GSTZ1-27656TH Recombinant Human GSTZ1, His-tagged E.coli His
Human GSTZ1-5707HCL Recombinant Human GSTZ1 293 Cell Lysate HEK293 N/A
Human GSTZ1-3370HF Recombinant Full Length Human GSTZ1 Protein, GST-tagged In Vitro Cell Free System GST 216 amino acids
Human GSTZ1-2157H Recombinant Human GSTZ1 protein, His-tagged E.coli His Met1-Ala216
Mouse Gstz1-1071M Recombinant Mouse Gstz1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat GSTZ1-2736R Recombinant Rat GSTZ1 Protein Mammalian Cell His
Rat GSTZ1-2390R Recombinant Rat GSTZ1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GSTZ1-2390R-B Recombinant Rat GSTZ1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey GSTZ1-582C Recombinant Cynomolgus GSTZ1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey GSTZ1-328C Recombinant Cynomolgus Monkey GSTZ1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey GSTZ1-328C-B Recombinant Cynomolgus Monkey GSTZ1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GSTZ1-609Z Recombinant Zebrafish GSTZ1 Mammalian Cell His
Chicken GSTZ1-4865C Recombinant Chicken GSTZ1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GSTZ1 Related Articles

GSTZ1 involved in several pathways and played different roles in them. We selected most pathways GSTZ1 participated on our site, such as Tyrosine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTZ1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Tyrosine metabolismALDH3B2;MIF;HPDA;MAOA;DCT;TAT;GOT1;PNMT;AOC2
Metabolic pathwaysGPI1;ITPKC;HSD17B6;ALLC;B4GALT6;PLA2G2F;PPAP2A;ST6GALNAC3;R05D11.9

GSTZ1 has several biochemical functions, for example, glutathione peroxidase activity, glutathione transferase activity, maleylacetoacetate isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTZ1 itself. We selected most functions GSTZ1 had, and list some proteins which have the same functions with GSTZ1. You can find most of the proteins on our site.

Function Related Protein
glutathione peroxidase activityGPX5;GPX4;MGST1;GSTZ1;CLIC2;GPX6;GPX4B;GPX4A;GPX2
glutathione transferase activityEEF1E1;GSTA3;GSTT4;GSTM6;HPGDS;GSTT2;GSTT1;GSTM;GSTM5
maleylacetoacetate isomerase activity
protein bindingMBD4;STRA13;ZNF41;SSSCA1;AURKAIP1;DLL1;ALOX5AP;NOL12;MBP
protein homodimerization activityCCDC103;TSG101;DMRTC2;TYRP1;AMICA1;PTPRE;SETMAR;C6orf108;GDF6

GSTZ1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTZ1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTZ1.

ABL1; FYN; NCK1; GRB2; PPP1CC

Sappl, PG; Onate-Sanchez, L; et al. Proteomic analysis of glutathione S-transferases of Arabidopsis thaliana reveals differential salicylic acid-induced expression of the plant-specific phi and tau classes. PLANT MOLECULAR BIOLOGY 54:205-219(2004).
Nadal-Wollbold, F; Pawlowski, M; et al. Platelet ERK2 activation by thrombin is dependent on calcium and conventional protein kinases C but not Raf-1 or B-Raf. FEBS LETTERS 531:475-482(2002).
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