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GTF2A1

  • Official Full Name

    general transcription factor IIA, 1, 19/37kDa

  • Overview

    Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II;(POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 (PubMed 8224848)).;One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD;subunits.
  • Synonyms

    GTF2A1; general transcription factor IIA, 1, 19/37kDa; glucose regulated protein, 58kD pseudogene; transcription initiation factor IIA subunit 1; TFIIA; General transcription factor IIA 1 19/37kDa; General transcription factor IIA1; Glucose regulated protein 58kD pseudogene; TF2A1; TFIIA 42; TFIIA alpha p55; TFIIA alpha p55, isoform 1; TFIIAL; TFIIA-42; OTTHUMP00000245978; OTTHUMP00000245980; TFIIA alpha, p55, isoform 1; general transcription factor IIA subunit 1; transcription initiation factor TFIIA 42;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GTF2A1-1172H Active Recombinant Human GTF2A1, P19, GST-tagged E.coli GST
Human GTF2A1-1170H Active Recombinant Human General Transcription Factor IIA, 1, 19/37kDa E.coli N/A
Human GTF2A1-1171H Active Recombinant Human GTF2A1, P12, GST-tagged E.coli GST
Human GTF2A1-1174H Active Recombinant Human General Transcription Factor IIA, 1, 19/37kDa, P12 E.coli N/A
Human GTF2A1-1173H Active Recombinant Human GTF2A1, P55, GST-tagged E.coli GST
Human GTF2A1-1175H Active Recombinant Human General Transcription Factor IIA, 1, 19/37kDa, P55 E.coli N/A
Human GTF2A1-8476H Active Recombinant Human GTF2A1/GTF2A2, His-tagged E.coli His
Human GTF2A1-13587H Recombinant Human GTF2A1, GST-tagged E.coli GST 1-330a.a.
Human GTF2A1-7865H Recombinant Human GTF2A1 protein, His & GST-tagged E.coli His/GST Ala2~Asp274 (Accession # P52655)
Human GTF2A1-27774TH Recombinant Human GTF2A1 E.coli N/A
Human GTF2A1-4437H Recombinant Human GTF2A1 Protein, GST-tagged Wheat Germ GST
Human GTF2A1-27776TH Recombinant Human GTF2A1, His-tagged E.coli His
Human GTF2A1-762HCL Recombinant Human GTF2A1 cell lysate N/A
Human GTF2A1-3373HF Recombinant Full Length Human GTF2A1 Protein, GST-tagged In Vitro Cell Free System GST 376 amino acids
Rat GTF2A1-2739R Recombinant Rat GTF2A1 Protein Mammalian Cell His
Rat GTF2A1-2393R-B Recombinant Rat GTF2A1 Protein Pre-coupled Magnetic Beads HEK293
Rat GTF2A1-2393R Recombinant Rat GTF2A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GTF2A1-2000R Recombinant Rhesus monkey GTF2A1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GTF2A1-1821R Recombinant Rhesus Macaque GTF2A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GTF2A1-1821R-B Recombinant Rhesus Macaque GTF2A1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GTF2A1-11933Z Recombinant Zebrafish GTF2A1 Mammalian Cell His
Chicken GTF2A1-2870C Recombinant Chicken GTF2A1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GTF2A1 involved in several pathways and played different roles in them. We selected most pathways GTF2A1 participated on our site, such as Basal transcription factors, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Basal transcription factorsTAF7;ERCC2;GTF2H2;TAF5;TAF6L;GTF2I;GTF2H4;GTF2H3;GTF2F2B
Viral carcinogenesisHIST1H4E;HDAC9;HIST1H4A;NFKB1;PIK3R1;REL;GTF2H2C;SCRIB;CCND3

GTF2A1 has several biochemical functions, for example, DNA binding, TBP-class protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2A1 itself. We selected most functions GTF2A1 had, and list some proteins which have the same functions with GTF2A1. You can find most of the proteins on our site.

Function Related Protein
DNA bindingNR4A2B;RABGAP1;SCMH1;DRAP1;MUS81;TXLNB;RREB1;POGZ;ISL2B
TBP-class protein bindingTAF1B;BRF1A;TAF1L;PSMC4;BRF1B;GTF2A1;GTF2A2;HHEX;PSMC5
protein bindingSPRYD7;RPL4;PPP2R5C;POLD4;ADM;HOXB5;SNRPB2;FMO4;ZBED3
protein heterodimerization activityPML;NFYB;HYPM;AHR;BMP6;SLC3A1;PDSS1;TENM3;CLNS1A
transcription coactivator activityUBE2L3;DDX5;GTF2F1;CRSP7;NCOA3;KDM5A;TFDP1;GRIP1;JUPA
transcription factor bindingGATA3;KCTD1;PDCD11;NFKBIA;RORA;PPRC1;TRAPPC2;KDM1A;MED12L

GTF2A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2A1.

GTF2A2; TBPL1; NFYA; TBP; SCHIP1; CREB1; Tbpl1

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