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GTF2H2C

Official Full Name

GTF2H2C general transcription factor IIH, polypeptide 2C [ Homo sapiens ]
Overview

This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). In brain studies, the encoded protein was found with the GRIP/AMPA receptor complex. Multiple alternatively spliced transcript variants have been described that encode different protein isoforms; however, the full-length nature and biological validity of all of these variants have not been determined.
Synonyms

general transcription factor IIH, polypeptide 2C; 31394; Ensembl:ENSG00000183474; FLJ77682, MGC102806, MGC198575, DKFZp686P18101; general transcription factor IIH subunit 2-like protein; general transcription factor IIH polypeptide 2-like protein;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GTF2H2C-13597H	Recombinant Human GTF2H2C, GST-tagged	E.coli	GST	1-395a.a.	$319 / 25ug
Human	GTF2H2C-2458H	Recombinant Human GTF2H2C Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	GTF2H2C-529H	Recombinant Human GTF2H2C Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein

GTF2H2C involved in several pathways and played different roles in them. We selected most pathways GTF2H2C participated on our site, such as Basal transcription factors, Nucleotide excision repair, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2H2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Basal transcription factors	TAF5L;GTF2F2;TAF5;TAF9;GTF2A1;TAF9B;TAF2;GTF2A1L;TAF1
Nucleotide excision repair	PCNA;POLE;RPA1;ZFP830;ERCC8;GTF2H2;COPS5;POLE3;RAD23A
Viral carcinogenesis	PXN;ACTN2;PMAIP1;DLG1;HIST1H2BD;HIST1H2BL;HIST1H4I;SRF;NRAS

GTF2H2C has several biochemical functions, for example, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2H2C itself. We selected most functions GTF2H2C had, and list some proteins which have the same functions with GTF2H2C. You can find most of the proteins on our site.

Function	Related Protein
protein binding	DHX30;TMEM59;ST13;TMEM31;VIL1;IRS1;ATP2C2;GM885;MAPRE2
zinc ion binding	EWSR1B;ADAMTSL1;RXRA;ASTL;LHX1B;MT1E;QPCTLA;MMP23BB;TTF2

GTF2H2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2H2C here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2H2C.

ERCC2; GTF2H3; DZIP3; SUV39H1