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GTF2H3

Official Full Name

general transcription factor IIH, polypeptide 3, 34kDa
Overview

GTF2H3 is a component of the core-TFIIHC basal transcription factor involved in nucleotide excision repair (NER) of DNA.
Synonyms

GTF2H3; general transcription factor IIH, polypeptide 3, 34kDa; general transcription factor IIH, polypeptide 3 (34kD subunit); general transcription factor IIH subunit 3; BTF2; TFIIH; BTF2 p34; basic transcription factor 2 34 kDa subunit; general transcription factor IIH polypeptide 3; TFIIH basal transcription factor complex p34 subunit; TFB4;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rat
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GTF2H3-4450H	Recombinant Human GTF2H3 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GTF2H3-13598H	Recombinant Human GTF2H3, His-tagged	E.coli	His	24-210a.a.	$319 / 25ug
Human	GTF2H3-5695HCL	Recombinant Human GTF2H3 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GTF2H3-3388HF	Recombinant Full Length Human GTF2H3 Protein, GST-tagged	In Vitro Cell Free System	GST	308 amino acids	Inquiry
Rat	GTF2H3-2744R	Recombinant Rat GTF2H3 Protein	Mammalian Cell	His		Inquiry
Rat	GTF2H3-2398R	Recombinant Rat GTF2H3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	GTF2H3-2398R-B	Recombinant Rat GTF2H3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	GTF2H3-685Z	Recombinant Zebrafish GTF2H3	Mammalian Cell	His		Inquiry
Chicken	GTF2H3-4910C	Recombinant Chicken GTF2H3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

GTF2H3 involved in several pathways and played different roles in them. We selected most pathways GTF2H3 participated on our site, such as Basal transcription factors, Nucleotide excision repair, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2H3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Basal transcription factors	TAF1L;TAF12;GTF2A1L;GTF2F2;GTF2H3;TAF8;TAF9B;GTF2F1;GTF2H4
Nucleotide excision repair	CHD1L;KIAA1530;MNAT1;GTF2H5;RAD23AB;COPS8;RFC3;RFC1;RPA4
Viral carcinogenesis	HIST1H2BF;HIST1H4L;TBP;HDAC10;SNW1;CASP8;MAPK3;RBL2;TRAF5

GTF2H3 has several biochemical functions, for example, contributes_to DNA-dependent ATPase activity, contributes_to RNA polymerase II carboxy-terminal domain kinase activity, damaged DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2H3 itself. We selected most functions GTF2H3 had, and list some proteins which have the same functions with GTF2H3. You can find most of the proteins on our site.

Function	Related Protein
contributes_to DNA-dependent ATPase activity	GTF2H4;ERCC2;MNAT1;GTF2H3;GTF2H1;GTF2H2;ERCC3;RBBP4;BPTF
contributes_to RNA polymerase II carboxy-terminal domain kinase activity	ERCC2;GTF2H2;GTF2H4;GTF2H1;MNAT1;ERCC3;GTF2H3
damaged DNA binding	RBBP8;POLK;RUVBL2;NEIL3;TRP53;XRCC1;FEN1;TRP63;ERCC3
metal ion binding	ZIC3;ZNF684;GGTA1;BGLAP2;ZFP292;PRG4B;ICN2;NPAS2;ADH8B
protein N-terminus binding	RBPJ;CHMP6;HAX1;STX5A;PEX19;ALOX5AP;DAXX;NIPBL;SNF8
protein binding	ZZZ3;SCIMP;HILPDA;PUS7L;WDR92;SF3A2;PLLP;RPL23A;CRELD2
contributes_to protein kinase activity	GTF2H1;GTF2H3;GTF2H4;GTF2H2;ERCC2;ERCC3
transcription factor activity, sequence-specific DNA binding	GTF3A;ZHX3;E2F4;ZHX2;ZFP879;ZFP629;ZNF131;FOXN2B;SMAD6A
translation factor activity, RNA binding	EIF4G1;CPEB2;GTF2H3;EIF5;EIF4G3;PPP1R2P9;EIF2S2;EEF2K;EIF4H

GTF2H3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2H3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2H3.

GTF2H2C; CDK7