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GTF2H4

  • Official Full Name

    general transcription factor IIH, polypeptide 4, 52kDa

  • Overview

    General transcription factor IIH subunit 4 is a protein that in humans is encoded by the GTF2H4 gene.
  • Synonyms

    GTF2H4; general transcription factor IIH, polypeptide 4, 52kDa; general transcription factor IIH, polypeptide 4 (52kD subunit); general transcription factor IIH subunit 4; TFB2; TFIIH; Basic transcription factor 2 52 kDa subunit; Basic transcription factor 52 kDa subunit; BTF2 p52; General transcription factor IIH polypeptide 4 52kDa; General transcription factor IIH polypeptide 4 52kDa subunit; General transcription factor IIH polypeptide 4 52kDa variant; General transcription factor IIH polypeptide 4; OTTHUMP00000029049; OTTHUMP00000164874; TF2H4_HUMAN; TFIIH basal transcription factor complex p52 subunit; TFIIH protein; TIFIIH; Transcription factor II H; Transcription factor IIH 52 kDa subunit;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GTF2H4-4452H Recombinant Human GTF2H4 Protein, GST-tagged Wheat Germ GST
Human GTF2H4-421H Recombinant Human GTF2H4 Protein, His-tagged E.coli His
Human GTF2H4-28282TH Recombinant Human GTF2H4 Wheat Germ N/A 100 amino acids
Human GTF2H4-5694HCL Recombinant Human GTF2H4 293 Cell Lysate HEK293 N/A
Human GTF2H4-3389HF Recombinant Full Length Human GTF2H4 Protein, GST-tagged In Vitro Cell Free System GST 462 amino acids
Mouse GTF2H4-7361M Recombinant Mouse GTF2H4 Protein Mammalian Cell His
Mouse GTF2H4-3991M Recombinant Mouse GTF2H4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GTF2H4-3991M-B Recombinant Mouse GTF2H4 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GTF2H4-2008R Recombinant Rhesus monkey GTF2H4 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GTF2H4-1829R-B Recombinant Rhesus Macaque GTF2H4 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GTF2H4-1829R Recombinant Rhesus Macaque GTF2H4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish GTF2H4-10294Z Recombinant Zebrafish GTF2H4 Mammalian Cell His
Chicken GTF2H4-2028C Recombinant Chicken GTF2H4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GTF2H4 Related Articles

GTF2H4 involved in several pathways and played different roles in them. We selected most pathways GTF2H4 participated on our site, such as Basal transcription factors, Nucleotide excision repair, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2H4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Basal transcription factorsTAF6;GTF2H2C;ERCC3;TAF5L;GTF2H3;TAF9B;TAF5;TBP;TAF6L
Nucleotide excision repairCOPS3;RFC4;INO80;GTF2H2C_2;RPA2;POLD4;RAD23AB;POLD1;COPS7A
Viral carcinogenesisCASP8;TRAF3;HDAC7;GTF2H2;YWHAZ;HIST1H4N;CREB5;ACTN4;CREB3L1

GTF2H4 has several biochemical functions, for example, ATP-dependent DNA helicase activity, contributes_to DNA-dependent ATPase activity, contributes_to RNA polymerase II carboxy-terminal domain kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2H4 itself. We selected most functions GTF2H4 had, and list some proteins which have the same functions with GTF2H4. You can find most of the proteins on our site.

Function Related Protein
ATP-dependent DNA helicase activityBRIP1;CHD2;XRCC6;DDX3X;CHST13;RUVBL2;CHD4;XRCC5;DHX9
contributes_to DNA-dependent ATPase activityGTF2H4;MNAT1;GTF2H3;RBBP4;BPTF;ERCC2;ERCC3;GTF2H2;GTF2H1
contributes_to RNA polymerase II carboxy-terminal domain kinase activityGTF2H4;ERCC2;MNAT1;GTF2H1;GTF2H3;ERCC3;GTF2H2
double-stranded DNA bindingHMGB2;MRE11A;SMAD2;YBX1;RAD51D;SP8B;XRCC2;TARDBP;XRCC6
protein bindingTMED10;KIF1B;LMLN;INVS;ARPIN;KIAA1967;UTP3;EP400;ATF6
contributes_to protein kinase activityGTF2H4;GTF2H2;GTF2H1;ERCC3;ERCC2;GTF2H3
transcription factor activity, sequence-specific DNA bindingSTAT1A;SOX13;ZNF192;FOXD5;CBFA2T2;PPARDB;NR2F1B;SNAPC5;HOXB6A

GTF2H4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2H4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2H4.

CDK7; Rpl35; GTF2H5

Kim, JY; Kim, JH; et al. Lack of association between GTF2H4 genetic variants and AERD development and FEV1 decline by aspirin provocation. INTERNATIONAL JOURNAL OF IMMUNOGENETICS 39:486-491(2012).
Buch, SC; Diergaarde, B; et al. Genetic variability in DNA repair and cell cycle control pathway genes and risk of smoking-related lung cancer. MOLECULAR CARCINOGENESIS 51:E11-E20(2012).
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