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GTPBP3

Official Full Name

GTP binding protein 3 (mitochondrial)
Overview

This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms

GTPBP3; GTP binding protein 3 (mitochondrial); tRNA modification GTPase GTPBP3, mitochondrial; FLJ14700; GTPBG3; MSS1; MTGP1; THDF1; GTP binding protein 3; GTP binding protein 3 mitochondrial; GTPBG 3; GTPBP 3; Mitochondrial GTP binding protein 1; Mitochondrial GTP binding protein; MSS 1; MTGP 1; THDF 1; tRNA modification GTPase GTPBP3; tRNA modification GTPase GTPBP3 mitochondrial; mitochondrial GTP-binding protein 1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

C
Myc
DDK
GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GTPBP3-4472H	Recombinant Human GTPBP3 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GTPBP3-5685HCL	Recombinant Human GTPBP3 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GTPBP3-299H	Recombinant Human GTPBP3 Protein, MYC/DDK-tagged, C13 and N15-labeled	HEK293	C-Myc/DDK		Inquiry
Human	GTPBP3-3424HF	Recombinant Full Length Human GTPBP3 Protein, GST-tagged	In Vitro Cell Free System	GST	492 amino acids	Inquiry
Mouse	Gtpbp3-3333M	Recombinant Mouse Gtpbp3 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rat	GTPBP3-2750R	Recombinant Rat GTPBP3 Protein	Mammalian Cell	His		Inquiry
Rat	GTPBP3-2404R	Recombinant Rat GTPBP3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	GTPBP3-2404R-B	Recombinant Rat GTPBP3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	GTPBP3-2909Z	Recombinant Zebrafish GTPBP3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
GTPBP3 Related Articles

GTPBP3 involved in several pathways and played different roles in them. We selected most pathways GTPBP3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GTPBP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

GTPBP3 has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTPBP3 itself. We selected most functions GTPBP3 had, and list some proteins which have the same functions with GTPBP3. You can find most of the proteins on our site.

Function	Related Protein
GTP binding	EEF2A.1;RALB;RASL11B;GNAT3;ARL2;GLUD2;TUBA4A;RAB11A;ARL13A
GTPase activity	MSTO1;RAB5B;EEF1A1L1;RAB1A;GNG3;GNAIA;RHOD;RAB40B;GNA12
protein binding	SMAD1;UVRAG;RIBC2;TRMT1;SIRT4;PLIN3;LAMTOR2;LCE3C;DNMT3A

GTPBP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTPBP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTPBP3.

PFKL; GNE; PRPF3; PTAFR; DCAF8; CIC; RIBC2; FAM60A; PARP11; IGHA1

Knorr, M; Hausding, M; et al. Nitroglycerin-Induced Endothelial Dysfunction and Tolerance Involve Adverse Phosphorylation and S-Glutathionylation of Endothelial Nitric Oxide Synthase Beneficial Effects of Therapy With the AT(1) Receptor Blocker Telmisartan. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 31:2223-U187(2011).

Kim, HR; Chae, HJ; et al. Mammalian dap3 is an essential gene required for mitochondrial homeostasis in vivo and contributing to the extrinsic pathway for apoptosis. FASEB JOURNAL 21:188-196(2007).

HAMASUR, B; GLASER, E; et al. PLANT MITOCHONDRIAL F0F1 ATP SYNTHASE - IDENTIFICATION OF THE INDIVIDUAL SUBUNITS AND PROPERTIES OF THE PURIFIED SPINACH LEAF MITOCHONDRIAL ATP SYNTHASE. EUROPEAN JOURNAL OF BIOCHEMISTRY 205:409-416(1992).

RODRIGUEZROSALES, MP; HERRIN, DL; et al. IDENTIFICATION OF LOW-MOLECULAR MASS GTP-BINDING PROTEINS IN MEMBRANES OF THE HALOTOLERANT ALGA DUNALIELLA-SALINA. PLANT PHYSIOLOGY 98:446-451(1992).