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GYPB

  • Official Full Name

    glycophorin B (MNS blood group)

  • Overview

    Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5 UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB.
  • Synonyms

    GYPB; glycophorin B (MNS blood group); glycophorin B (includes Ss blood group) , glycophorin B (Ss blood group) , MNS; glycophorin-B; CD235b; GPB; SS; GLPB_HUMAN; PAS-3; Sialoglycoprotein delta; SS-active sialoglycoprotein; Ss blood group; glycophorin HeP2; glycophorin MiVI; MNS; GPB.NY; HGpMiVI; GYPHe.NY;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Homo sapiens (Human)
  • Human
  • Pan troglodytes (Chimpanzee)
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • In vitro E. coli expression system
  • Mammalian cells
  • Wheat Germ
  • C
  • Fc
  • GST
  • His
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GYPB-4509H Recombinant Human GYPB Protein Wheat Germ N/A
Human GYPB-4510H Recombinant Human GYPB Protein, GST-tagged Wheat Germ GST
Human GYPB-313HCL Recombinant Human GYPB lysate HEK293 N/A
Human GYPB-3376HF Recombinant Full Length Human GYPB Protein In Vitro Cell Free System 720 amino acids
Human GYPB-4288H Recombinant Human GYPB Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 20-91aa
Human GYPB-3066H Recombinant Human GYPB Protein (Met1-Ala59), C-Fc tagged Mammalian cells C-Fc Met1-Ala59
Homo sapiens (Human) RFL14875HF Recombinant Full Length Human Glycophorin-B(Gypb) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (20-91aa)
Pan troglodytes (Chimpanzee) RFL10312PF Recombinant Full Length Pan Troglodytes Glycophorin-B(Gypb) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (20-123)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GYPB Related Articles

GYPB involved in several pathways and played different roles in them. We selected most pathways GYPB participated on our site, such as Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with GYPB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MalariaHBB;LRP1;IL6;MET;HBB-B2;HBA-A2;SDC1;CD81;VCAM1

GYPB has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GYPB itself. We selected most functions GYPB had, and list some proteins which have the same functions with GYPB. You can find most of the proteins on our site.

Function Related Protein
protein bindingSULT2B1;BSCL2;PPP1CC;FOXRED2;CPEB3;DACT2;PPIH;MYCBP;HTATIP2

GYPB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GYPB here. Most of them are supplied by our site. Hope this information will be useful for your research of GYPB.

UBQLN1; UBQLN1

Hsu, K; Lin, YC; et al. A direct blood polymerase chain reaction approach for the determination of GP.Mur (Mi.III) and other Hil plus Miltenberger glycophorin variants. TRANSFUSION 53:962-971(2013).
Peyrard, T; Lam, Y; et al. Anti-U-like as an alloantibody in S-s-U- and S-s-U+(var) black people. TRANSFUSION 52:622-628(2012).
  • Q&As
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