Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Gna12

  • Official Full Name

    guanine nucleotide binding protein (G protein) alpha 12

  • Overview

    RMP (RPB5-Mediating Protein), also known as URI (Unconventional prefoldin RBP5 Interactor), was described as an unconventional member of the prefoldin (PFD) family of chaperones that are involved in actin and tubulin folding. Like conventional members of
  • Synonyms

    GNA12; guanine nucleotide binding protein (G protein) alpha 12; guanine nucleotide-binding protein subunit alpha-12; gep; g alpha-12; WUGSC:H_GS165O14.2; G-protein subunit alpha-12; RMP; NNX3; MGC99644; MGC104623;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GNA12-719HCL Recombinant Human GNA12 cell lysate N/A
Mouse GNA12-7010M Recombinant Mouse GNA12 Protein Mammalian Cell His
Mouse Gna12-4277M Recombinant Mouse Gna12 protein, His&Myc-tagged E.coli His&Myc 1-379aa
Mouse GNA12-3753M-B Recombinant Mouse GNA12 Protein Pre-coupled Magnetic Beads HEK293
Mouse GNA12-3753M Recombinant Mouse GNA12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Gna12 Related Articles

Gna12 involved in several pathways and played different roles in them. We selected most pathways Gna12 participated on our site, such as MAPK signaling pathway, cGMP-PKG signaling pathway, Sphingolipid signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Gna12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayFGF13B;FGF6;JUND;GRB2B;MAP2K6;FGF10;MAP4K1;GADD45BB;DUSP16
cGMP-PKG signaling pathwayNPR2;MYLK3;SLC25A6;GNAI2;NFATC2;ATP1B2;PDE2A;GTF2I;MEF2D
Sphingolipid signaling pathwayMAPK3;SPHK1;BCL2;PIK3CD;NFKB1;DEGS1;GNA12;PRKCG;PPP2R2B
Phospholipase D signaling pathwaySHC3;CYTH2;CYTH3;SYK;CYTH1;PLCB3;Kitl;GRM3;KIT
Vascular smooth muscle contractionRHOAD;PLA2G2E;KCNMB3;PLA2G4A;ROCK2A;PPP1R12B;ACTG2;PPP1R14AB;MAPK1
Long-term depressionPLA2G4F;IGF1;IGF1R;PLA2G4A;MAPK1;PLCB4;GNAQ;GRIA1;GUCY1B3
Regulation of actin cytoskeletonSSH1;NCKAP1L;MYL2;PIK3R2;FGFR4;FGF10A;WASLA;CDC42L2;ARPC5B
Pathways in cancerCSF1R;STK4;FGFR2;KIT;TCF7L2;NOS2;PIK3R2;TRP53;RXRA

Gna12 has several biochemical functions, for example, D5 dopamine receptor binding, G-protein beta/gamma-subunit complex binding, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Gna12 itself. We selected most functions Gna12 had, and list some proteins which have the same functions with Gna12. You can find most of the proteins on our site.

Function Related Protein
D5 dopamine receptor bindingGNA13B;GNA12;GNA13;GNA13A;GNA12A
G-protein beta/gamma-subunit complex bindingGNA13;GNA11A;GNAO1;CETN1;GNAV1;GNAI3;CETN4;GNAS;GNA14
GTP bindingARL4AB;GBP1;AGAP1;GNL2;SEPT11;GEM;TUBD1;EIF2S3;RASL10A
GTPase activityGNG11;RRAGD;RAB35B;RAB1BA;GTPBP10;EEFSEC;TUBG2;OPA1;GNA11B
metal ion bindingAGFG1B;ZFP82;FBXO5;EPT1;PM20D1;FCN1;ATP9B;GZF1;ZFP322A
protein bindingGALT;PRPSAP1;PPP1R8;PPARD;SCUBE3;HIST1H1C;G3BP2;E4F1;FOXP4
signal transducer activityGNG2;BAI2;GPR132;TAAR14D;TAS2R110;OLFCG2;SLC20A1;STAT2;HTR5AL

Gna12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Gna12 here. Most of them are supplied by our site. Hope this information will be useful for your research of Gna12.

PPP2R1A; IL3RA; q81v40_bacan; 15-deoxy-delta(12,14; ARHGEF1

Rasheed, SAK; Teo, CR; et al. MicroRNA-182 and MicroRNA-200a Control G-protein Subunit alpha-13 (GNA13) Expression and Cell Invasion Synergistically in Prostate Cancer Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 288:7986-7995(2013).
Jia, PL; Wang, LL; et al. Network-Assisted Investigation of Combined Causal Signals from Genome-Wide Association Studies in Schizophrenia. PLOS COMPUTATIONAL BIOLOGY 8:-(2012).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All Gna12 Products

Required fields are marked with *

My Review for All Gna12 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends