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GPC1

  • Official Full Name

    glypican 1

  • Overview

    Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage.These proteins may play a role in the control of cell division and growth regulation.
  • Synonyms

    GPC1; glypican 1; glypican-1; glypican; glypican proteoglycan 1; FLJ38078; glypican1; GPC 1; GPC1_HUMAN; Secreted glypican-1; OTTHUMP00000164497; OTTHUMP00000201548;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • human|IgG1|Fc
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GPC1-152H Active Recombinant Human Glypican 1, His-tagged Mammalian cells His
Human GPC1-29027TH Recombinant Human GPC1 Wheat Germ N/A 108 amino acids
Human GPC1-5761H Recombinant Human GPC1 protein, His-tagged E.coli His Leu114~Lys277
Human GPC1-3058H Recombinant Human GPC1 Protein (Asp24-Thr529), N-His tagged Mammalian cells N-His Asp24-Thr529
Human GPC1-5145H Recombinant Human GPC1 Protein, GST-tagged Wheat Germ GST
Human GPC1-624H Recombinant Human GPC1 protein, Fc-tagged HEK293 human/IgG1/Fc Asp24-Ser530
Human GPC1-2064H Recombinant Human GPC1 protein, His-tagged HEK293 His Asp24-Ser530
Human GPC1-3056H Recombinant Human GPC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GPC1-3057H Recombinant Human GPC1 Protein (Asp24-Ser529), C-His tagged Mammalian cells C-His Asp24-Ser529
Human GPC1-1430H Recombinant Human GPC1 protein, His-GST & Myc-tagged E.coli His-GST & Myc 342-530aa
Human GPC1-1283H Active Recombinant Human GPC1 protein, His-tagged HEK293 His Asp24-Gln527
Human GPC1-3056H-B Recombinant Human GPC1 Protein Pre-coupled Magnetic Beads HEK293
Human GPC1-3059H Recombinant Human GPC1 Protein (Glu208-Ser530), N-His tagged E.coli N-His Glu208-Ser530
Mouse Gpc1-153M Active Recombinant Mouse Gpc1 protein, His-tagged Mammalian cells His Asp24-Ser529
Mouse Gpc1-154M Recombinant Mouse Gpc1 protein, His-tagged HEK293 His Asp24-Ser529
Mouse Gpc1-5762M Recombinant Mouse Gpc1 protein, His-tagged E.coli His Gly343~Val545 (Accession # Q9QZF2)
Mouse Gpc1-3821M Recombinant Mouse Gpc1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Gpc1-3821M-B Recombinant Mouse Gpc1 Protein Pre-coupled Magnetic Beads HEK293
Rat GPC1-2631R Recombinant Rat GPC1 Protein Mammalian Cell His
Rat GPC1-2286R-B Recombinant Rat GPC1 Protein Pre-coupled Magnetic Beads HEK293
Rat GPC1-2286R Recombinant Rat GPC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GPC1-1930R Recombinant Rhesus monkey GPC1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GPC1-1750R-B Recombinant Rhesus Macaque GPC1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GPC1-1750R Recombinant Rhesus Macaque GPC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GPC1 Related Articles

GPC1 involved in several pathways and played different roles in them. We selected most pathways GPC1 participated on our site, such as Proteoglycans in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Proteoglycans in cancerCBL;FAS;MMP9;MET;MAP2K2;PRKCG;ERBB2;WNT5B;FLNC

GPC1 has several biochemical functions, for example, copper ion binding, fibroblast growth factor binding, heparan sulfate proteoglycan binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPC1 itself. We selected most functions GPC1 had, and list some proteins which have the same functions with GPC1. You can find most of the proteins on our site.

Function Related Protein
copper ion bindingABHD1;PAM;SNCA;SCO2;HEPHL1A;DBH;SNAI3;IL1A;LOXL5A
fibroblast growth factor bindingFGFRL1;FGFR4;FGFR3;KLB;RPS2;FGFR2;GLG1B;THBS1;S100A13
heparan sulfate proteoglycan bindingGPC4;SEMA5A;GPC3;Gpc2;AGRN;HRG;FST;GPC1B;GPC6A
laminin bindingECM1;ITGA3;NCL;GPC1;THBS1;LYPD5;ACHE;AGRN;BCAM

GPC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPC1.

TDGF1; PECAM1; FSTL1; Cbx1; Prkci; Mad2l1

Ullah, M; Sittinger, M; et al. Extracellular matrix of adipogenically differentiated mesenchymal stem cells reveals a network of collagen filaments, mostly interwoven by hexagonal structural units. MATRIX BIOLOGY 32:452-465(2013).
Kayed, H; Kleeff, J; et al. Correlation of glypican-1 expression with TGF-beta, BMP, and activin receptors in pancreatic ductal adenocarcinoma. INTERNATIONAL JOURNAL OF ONCOLOGY 29:1139-1148(2006).
RUSSELL, DA; SACHS, MM; et al. THE MAIZE CYTOSOLIC GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE GENE FAMILY - ORGAN-SPECIFIC EXPRESSION AND GENETIC-ANALYSIS. MOLECULAR & GENERAL GENETICS 229:219-228(1991).
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