Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the most telomeric copy.
H2AFB3; H2A histone family, member B3; H2A histone family, member B , H2AFB; histone H2A-Bbd type 2/3; H2A Barr body deficient; H2A histone family member B; H2ABBD; H2AFB; Histone H2A BBD; H2A.Bbd; H2A Barr body-deficient; histone variant H2A, Barr-body deficient; H2AFB2
H2AFB3 involved in several pathways and played different roles in them. We selected most pathways H2AFB3 participated on our site, such as Alcoholism, Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with H2AFB3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
H2AFB3 has several biochemical functions, for example, DNA binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by H2AFB3 itself. We selected most functions H2AFB3 had, and list some proteins which have the same functions with H2AFB3. You can find most of the proteins on our site.
Function DNA binding
Related Protein POLR3A; DMBX1A; NKX6.3; MLL1; NEUROD6A; HOXC3A; NTNG1; HOXB13A; OTPB; SP8B
Function protein heterodimerization activity
Related Protein UGT1A4; SPNA1; NFYC; SLC51A; CHRAC1; BMP2B; BOKA; SMAD4; HYPM; H2-Q10