Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

H2AFY

  • Official Full Name

    H2A histone family, member Y

  • Overview

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Synonyms

    H2AFY; H2A histone family, member Y; core histone macro-H2A.1; macroH2A1.2; Core histone macro h2a.1; H2A histone family member Y; H2A.y; H2A/y; Histone macroH2A1; Histone macroH2A1.1; Histone macroH2A1.2; Macroh2a1; Medulloblastoma antigen MU MB 50.205; mH2a; mH2A1; histone H2A.y; OTTHUMP00000159413; OTTHUMP00000223174; OTTHUMP00000223175; OTTHUMP00000223176; medulloblastoma antigen MU-MB-50.205; H2AFJ; H2AF12M; MACROH2A1.1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • HIS
  • His (Fc)
  • Avi
  • His|GST
  • N/A
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human H2AFY-117H Recombinant Human H2AFY protein, T7/His-tagged E.coli T7/His
Human H2AFY-133H Recombinant Human H2AFY Protein, HIS-tagged E.coli HIS
Human H2AFY-4538H Recombinant Human H2AFY Protein, GST-tagged Wheat Germ GST
Human H2AFY-5658HCL Recombinant Human H2AFY 293 Cell Lysate HEK293 N/A
Human H2AFY-5657HCL Recombinant Human H2AFY 293 Cell Lysate HEK293 N/A
Human H2AFY-3404HF Recombinant Full Length Human H2AFY Protein, GST-tagged In Vitro Cell Free System GST 372 amino acids
Human H2AFY-1705H Recombinant Human H2AFY protein, His & GST-tagged E.coli His/GST Ile109~Asn369 (Accession # O75367)
Rat H2AFY-2776R Recombinant Rat H2AFY Protein Mammalian Cell His
Rat H2AFY-2430R Recombinant Rat H2AFY Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat H2AFY-2430R-B Recombinant Rat H2AFY Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque H2AFY-2028R Recombinant Rhesus monkey H2AFY Protein, His-tagged Mammalian Cell His
Rhesus Macaque H2AFY-1849R-B Recombinant Rhesus Macaque H2AFY Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque H2AFY-1849R Recombinant Rhesus Macaque H2AFY Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish H2AFY-3784Z Recombinant Zebrafish H2AFY Mammalian Cell His
Chicken H2AFY-6565C Recombinant Chicken H2AFY Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • H2AFY Related Research Area

H2AFY involved in several pathways and played different roles in them. We selected most pathways H2AFY participated on our site, such as Alcoholism, Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with H2AFY were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
AlcoholismHIST1H2BJ;CALML5;GNG11;GRIN1;HIST1H2AB;HIST1H4G;HDAC5;HIST1H2BP;HIST3H2BB
Systemic lupus erythematosusSNRPB;HLA-DRA;C1R;H3F3A;HIST1H4K;C8A;HLA-DRB4;HIST1H2BQ;FCGR4

H2AFY has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by H2AFY itself. We selected most functions H2AFY had, and list some proteins which have the same functions with H2AFY. You can find most of the proteins on our site.

Function Related Protein
DNA bindingSP100;E2F1;RAD51C;ZFP92;EEPD1;INSM1B;HOXA13A;CRAMP1L;DMTF1
RNA polymerase II core promoter sequence-specific DNA bindingGBX2;H2AFZ;SUZ12;SFPI1;TAL1;NLRC5;ZNF277;HOXB3;H3F3B
RNA polymerase II regulatory region sequence-specific DNA bindingZSCAN20;BARHL1B;PRKCBP1L;JARID2;H2AFY;MEF2C;CGGBP1;E4F1;TAL1
chromatin DNA bindingVAX1;ACTN4;XBP1;NEUROG3;HIST1H1E;EZH2;GRHL1;HIST1H1B;GATA1
core promoter sequence-specific DNA bindingSOX9;THRAP3;CREM;SP1;ESR2;CRY1;NR1D1;SOHLH2;MTA1
double-stranded methylated DNA bindingMBD1;MECP2;H2AFY
nucleosomal DNA bindingHMGA2;H2AFY;H3F3A;HMGN5;HMGN4;RCC1;HMGN1;HMGN2;H3F3C
protein bindingMAP1B;RPS27A;KRTAP4-2;USP44;GABBR2;SLIRP;C1orf21;BTC;CTBP1
protein heterodimerization activityCRLF1;TCF12;GTF2A1;THRA;HIST1H2B8;UGT1A1;USF1;WHRN;HIST1H2BF
protein kinase bindingTBC1D14;LIPE;HDAC4;ADCY6;GDF3;RB1CC1;LATS1;MAG;SQSTM1
protein serine/threonine kinase inhibitor activityCIB1;SPRY2;H2AFY;SPRED1;SPRED2
rDNA bindingH2AFY;BEND3;GTF2H5
transcription regulatory region DNA bindingKCNA3;TRP53;ZNF217;RNF10;BCL11AA;IKZF4;GATA4;DHX36;ZNF174

H2AFY has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with H2AFY here. Most of them are supplied by our site. Hope this information will be useful for your research of H2AFY.

ERICH2; ERBB2; ATF2; SRPK1; q7chd7_yerpe; yapB; PARP1; VCAM1; CD247; ATRX

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All H2AFY Products

Required fields are marked with *

My Review for All H2AFY Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends