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HMGN3

  • Official Full Name

    high mobility group nucleosomal binding domain 3

  • Overview

    Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    HMGN3; high mobility group nucleosomal binding domain 3; thyroid hormone receptor interactor 7 , TRIP7; high mobility group nucleosome-binding domain-containing protein 3; DKFZp686E20226; FLJ42187; HMGN3_HUMAN; OTTHUMP00000016772; OTTHUMP00000016773; PNAS 24; PNAS 25; PNAS24; PNAS25; Thyroid hormone receptor interacting protein 7; Thyroid receptor-interacting protein 7; TR-interacting protein 7; TRIP 7; TRIP-7; TRIP7; PNAS-24; PNAS-25;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HMGN3-7380H Recombinant Human HMGN3 protein, His-tagged E.coli His Met1-Asn77
Human HMGN3-524H Recombinant Human HMGN3 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HMGN3-525H Recombinant Human HMGN3 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HMGN3-4881H Recombinant Human HMGN3 Protein, GST-tagged Wheat Germ GST
Human HMGN3-5472HCL Recombinant Human HMGN3 293 Cell Lysate HEK293 N/A
Human HMGN3-2468H Recombinant Human HMGN3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HMGN3-7955HFL Recombinant Full Length Human HMGN3 protein, Flag-tagged Mamanlian cells Flag
Human HMGN3-3661HF Recombinant Full Length Human HMGN3 Protein, GST-tagged In Vitro Cell Free System GST 77 amino acids
Human HMGN3-2247H Recombinant Human HMGN3 Protein, His-tagged E.coli N-His Met1-Glu99
Mouse HMGN3-7738M Recombinant Mouse HMGN3 Protein Mammalian Cell His
Mouse Hmgn3-1629M Recombinant Mouse Hmgn3 Protein, His-tagged E.coli N-His Met1-Glu99
Mouse HMGN3-4245M Recombinant Mouse HMGN3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hmgn3-3415M Recombinant Mouse Hmgn3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse HMGN3-4245M-B Recombinant Mouse HMGN3 Protein Pre-coupled Magnetic Beads HEK293
Rat HMGN3-2870R Recombinant Rat HMGN3 Protein Mammalian Cell His
Rat HMGN3-2525R-B Recombinant Rat HMGN3 Protein Pre-coupled Magnetic Beads HEK293
Rat HMGN3-2525R Recombinant Rat HMGN3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish HMGN3-1703Z Recombinant Zebrafish HMGN3 Mammalian Cell His
Chicken HMGN3-1554C Recombinant Chicken HMGN3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HMGN3 Related Articles

HMGN3 involved in several pathways and played different roles in them. We selected most pathways HMGN3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HMGN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

HMGN3 has several biochemical functions, for example, nucleosomal DNA binding, thyroid hormone receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HMGN3 itself. We selected most functions HMGN3 had, and list some proteins which have the same functions with HMGN3. You can find most of the proteins on our site.

Function Related Protein
nucleosomal DNA bindingHMGN1;H3F3A;H2AFZ;HMGN5;HMGN2;HMGN3;NSBP1;HNRNPC;RCC1
thyroid hormone receptor bindingMED24;MED17;TRIP6;OASL;MED30;HMGN3;PRMT2;MED16;NR0B2

HMGN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HMGN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of HMGN3.

SRPK2; SRPK1; GRB2; SMAD2; TERF1; TERF2; ycdQ; TERF2IP; p27958-pro_0000037566; Csnk1d

Chekmareva, NY; Sotnikov, SV; et al. Environmental manipulations generate bidirectional shifts in both behavior and gene regulation in a crossbred mouse model of extremes in trait anxiety. FRONTIERS IN BEHAVIORAL NEUROSCIENCE 8:-(2014).
Kugler, JE; Horsch, M; et al. High Mobility Group N Proteins Modulate the Fidelity of the Cellular Transcriptional Profile in a Tissue- and Variant-specific Manner. JOURNAL OF BIOLOGICAL CHEMISTRY 288:16690-16703(2013).
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