HPX
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Official Full Name
hemopexin
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Overview
This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. -
Synonyms
HPX; hemopexin; Beta 1B glycoprotein; Beta-1B-glycoprotein; FLJ56652; HEMO; HEMO_HUMAN; HX; OTTHUMP00000164583;
- Recombinant Proteins
- Cell & Tissue Lysates
- Native Proteins
- Transfected Stable Cell Lines
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Human
- Human Cell
- Human Plasma
- Human Serum or Plasma
- In Vitro Cell Free System
- Mammalian Cell
- Rat Serum
- Wheat Germ
- Yeast
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- HPX Related Articles
- HPX Related Research Area
HPX involved in several pathways and played different roles in them. We selected most pathways HPX participated on our site, such as Binding and Uptake of Ligands by Scavenger Receptors, Scavenging of heme from plasma, Vesicle-mediated transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with HPX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Binding and Uptake of Ligands by Scavenger Receptors | NFX1;HSPH1;COL1A2;COL3A1;LOC479668;HP;HYOU1;COL1A1;Alb |
Scavenging of heme from plasma | CD163;AMBP;HPX;NFX1;HP;LOC479668 |
Vesicle-mediated transport | HYOU1;SNX9B;PPP6R3;GJA4;HPX;COPB2;AP3S1;STAB2;TBC1D8B |
HPX has several biochemical functions, for example, heme transporter activity, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HPX itself. We selected most functions HPX had, and list some proteins which have the same functions with HPX. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
heme transporter activity | FLVCR1;HRG-1;SLC48A1;ABCG2;HPX;SLC48A1A;SLC48A1B;MFSD7B;ABCB7 |
metal ion binding | ZKSCAN1;ZNF404;GUCY1B3;FGD;YY1A;ZBTB44;MLPH;ZNF330;LONRF1L |
protein binding | MAGEC2;MPZL2B;COQ7;ALS2;MR1;ZBTB17;SIL1;MYLIPA;TTF2 |
HPX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPX here. Most of them are supplied by our site. Hope this information will be useful for your research of HPX.
GLUD1; TP63; LTN1; ALB
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, low levels of HPX in the blood can be an indicator of hemolytic disorders.
HPX binds to free heme released from hemoglobin, preventing its toxic effects and aiding in its clearance.
HPX binds to heme, preventing its oxidative and inflammatory damage to tissues and organs.
Hemolysis, hemoglobinopathies, and various types of anemias can lead to heme release, highlighting the clinical relevance of HPX.
HPX levels can be influenced by various factors, including inflammation and medications like glucocorticoids.
Customer Reviews (3)
Write a reviewthe manufacturer offers a wide range of HPX protein variants, including recombinant or native forms, as well as different conjugates and modifications.
As a researcher using HPX protein, I have found numerous advantages in its application during trials for various experimental purposes.
the HPX protein is known for its strong affinity for phospholipids, particularly phosphatidylserine (PS), on the outer leaflet of cell membranes.
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