HTRA2
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Official Full Name
HtrA serine peptidase 2
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Overview
High temperature requirement protein A2 (HtrA2)/Omi is a serine protease with homology to the E. coli HtrA protein (DegP) and is thought to be involved in apoptosis and stress-induced degradation of misfolded proteins. While HtrA2 was orignally identified -
Synonyms
HTRA2; HtrA serine peptidase 2; protease, serine, 25 , PRSS25; serine protease HTRA2, mitochondrial; OMI; PARK13; serine protease 25; protease, serine, 25; serine proteinase OMI; HtrA-like serine protease; Omi stress-regulated endoprotease; high temperatu;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Drosophila ananassae (Fruit fly)
- Drosophila erecta (Fruit fly)
- Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)
- Drosophila melanogaster (Fruit fly)
- Drosophila mojavensis (Fruit fly)
- Drosophila persimilis (Fruit fly)
- Drosophila pseudoobscura pseudoobscura (Fruit fly)
- Drosophila sechellia (Fruit fly)
- Drosophila simulans (Fruit fly)
- Drosophila virilis (Fruit fly)
- Drosophila willistoni (Fruit fly)
- Drosophila yakuba (Fruit fly)
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rhesus Macaque
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- Mammalian cells
- C
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | HTRA2-968H | Active Recombinant Human HTRA2 protein, His-tagged | E.coli | His | Ala134-Glu458 | |
Human | HTRA2-1144H | Recombinant Human HTRA2, His tagged | E.coli | His | ||
Human | HTRA2-26086TH | Recombinant Human HTRA2, His-tagged | E.coli | His | ||
Human | HTRA2-26919TH | Recombinant Human HTRA2, His-tagged | E.coli | His | ||
Human | HTRA2-56H | Recombinant Human HtrA Serine Peptidase 2, His-tagged | E.coli | His | ||
Human | HTRA2-14010H | Recombinant Human HTRA2, His-tagged | E.coli | His | 133-458a.a. | |
Human | HTRA2-2589H | Active Recombinant Human HTRA2 protein | E.coli | N/A | Ala134-Glu458 | |
Human | HTRA2-3491H | Recombinant Human HTRA2 Protein (Ala134-Glu458), C-His tagged | Mammalian cells | C-His | Ala134-Glu458 | |
Mouse | HTRA2-7943M | Recombinant Mouse HTRA2 Protein | Mammalian Cell | His | ||
Mouse | HTRA2-4382M-B | Recombinant Mouse HTRA2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | HTRA2-4382M | Recombinant Mouse HTRA2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Bos taurus (Bovine) | RFL19688BF | Recombinant Full Length Bovine Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (134-458) | |
Drosophila ananassae (Fruit fly) | RFL2960DF | Recombinant Full Length Drosophila Ananassae Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (79-426) | |
Drosophila erecta (Fruit fly) | RFL22122DF | Recombinant Full Length Drosophila Erecta Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (75-422) | |
Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi) | RFL28413DF | Recombinant Full Length Drosophila Grimshawi Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (79-426) | |
Drosophila melanogaster (Fruit fly) | RFL8310DF | Recombinant Full Length Drosophila Melanogaster Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (94-422) | |
Drosophila mojavensis (Fruit fly) | RFL25212DF | Recombinant Full Length Drosophila Mojavensis Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (83-430) | |
Drosophila persimilis (Fruit fly) | RFL1164DF | Recombinant Full Length Drosophila Persimilis Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (78-427) | |
Drosophila pseudoobscura pseudoobscura (Fruit fly) | RFL16301DF | Recombinant Full Length Drosophila Pseudoobscura Pseudoobscura Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (78-427) | |
Drosophila sechellia (Fruit fly) | RFL9385DF | Recombinant Full Length Drosophila Sechellia Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (75-422) | |
Drosophila simulans (Fruit fly) | RFL18179DF | Recombinant Full Length Drosophila Simulans Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (75-422) | |
Drosophila virilis (Fruit fly) | RFL20337DF | Recombinant Full Length Drosophila Virilis Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (74-421) | |
Drosophila willistoni (Fruit fly) | RFL19142DF | Recombinant Full Length Drosophila Willistoni Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (85-434) | |
Drosophila yakuba (Fruit fly) | RFL16820DF | Recombinant Full Length Drosophila Yakuba Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (75-422) | |
Homo sapiens (Human) | RFL26686HF | Recombinant Full Length Human Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (134-458) | |
Mus musculus (Mouse) | RFL34599MF | Recombinant Full Length Mouse Serine Protease Htra2, Mitochondrial(Htra2) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (134-458) | |
Rhesus Macaque | HTRA2-2178R | Recombinant Rhesus monkey HTRA2 Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | HTRA2-1999R-B | Recombinant Rhesus Macaque HTRA2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rhesus Macaque | HTRA2-1999R | Recombinant Rhesus Macaque HTRA2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
- Involved Pathway
- Protein Function
- Interacting Protein
- HTRA2 Related Articles
- HTRA2 Related Research Area
HTRA2 involved in several pathways and played different roles in them. We selected most pathways HTRA2 participated on our site, such as Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with HTRA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Parkinsons disease | NDUFA5;LRRK2;UQCR10;NDUFB3;UBE2G2;SLC18A1;APAF1;NDUFS4;UBE2J2 |
HTRA2 has several biochemical functions, for example, peptidase activity, protein binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HTRA2 itself. We selected most functions HTRA2 had, and list some proteins which have the same functions with HTRA2. You can find most of the proteins on our site.
Function | Related Protein |
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peptidase activity | PLAUA;KLK7;USP27X;MPND;CTSLL;ADAM25;SPG7;REN2;CTSH |
protein binding | CCK;PRPF40A;FABP2;MAGEE1;SHC1;MAP1S;ZFP110;TFF3;ZBTB4 |
serine-type endopeptidase activity | LOC100686744;PCSK4;F7I;PRSS33;KLK1B24;Gzmg;F9A;TPSB2;GZME |
serine-type peptidase activity | OVCH2;PRSS59.1;DPP7;TMPRSS2;TMPRSS11E;TMPRSS13A;PRSS40;F9A;Prss32 |
unfolded protein binding | GRPEL1;CRYABB;DNAJB11;CCT2;TRAP1;HSP90AB1;CDC37;AIP;NPM1 |
HTRA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HTRA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HTRA2.
XIAP
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