HYAL3
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Official Full Name
hyaluronoglucosaminidase 3
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Overview
This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. -
Synonyms
HYAL3; hyaluronoglucosaminidase 3; hyaluronidase-3; LUCA 3; LUCA14; Minna14; Hyal-3; HYAL3_HUMAN; Hyaluronidase 3; Hyaluronoglucosaminidase-3; LUCA-3; LUCA3; Lung carcinoma protein 3; OTTHUMP00000211052; OTTHUMP00000211054; OTTHUMP00000219781;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | HYAL3-14020H | Recombinant Human HYAL3, His-tagged | E.coli | His | 1-350a.a. | |
Human | HYAL3-831HCL | Recombinant Human HYAL3 cell lysate | N/A | |||
Human | HYAL3-5220H | Recombinant Human HYAL3 Protein, GST-tagged | Wheat Germ | GST | ||
Human | HYAL3-5727HF | Recombinant Full Length Human HYAL3 Protein, GST-tagged | In Vitro Cell Free System | GST | 417 amino acids | |
Mouse | HYAL3-7954M | Recombinant Mouse HYAL3 Protein | Mammalian Cell | His | ||
Mouse | HYAL3-4390M | Recombinant Mouse HYAL3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | HYAL3-4390M-B | Recombinant Mouse HYAL3 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | HYAL3-2976R | Recombinant Rat HYAL3 Protein | Mammalian Cell | His | ||
Rat | HYAL3-2631R-B | Recombinant Rat HYAL3 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | HYAL3-2631R | Recombinant Rat HYAL3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Zebrafish | HYAL3-6839Z | Recombinant Zebrafish HYAL3 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- HYAL3 Related Articles
HYAL3 involved in several pathways and played different roles in them. We selected most pathways HYAL3 participated on our site, such as Glycosaminoglycan degradation, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with HYAL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Glycosaminoglycan degradation | HPSE;HYAL1;GNSB;HEXB;GALNS;NAGLU;HGSNAT;GNSA;ARSB |
Metabolic pathways | NDUFS6;ALDH7A1;UQCRC2A;CYP4F2;ALG2;ACADS;CYP2A12;MGAT3A;AKR1B1L |
HYAL3 has several biochemical functions, for example, hyaluronoglucuronidase activity, hyalurononglucosaminidase activity, NOT hyalurononglucosaminidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HYAL3 itself. We selected most functions HYAL3 had, and list some proteins which have the same functions with HYAL3. You can find most of the proteins on our site.
Function | Related Protein |
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hyaluronoglucuronidase activity | HYAL2;HYAL3 |
hyalurononglucosaminidase activity | HYAL2;HYAL1;HYAL3;HYAL4;SPAM1;MGEA5;CD44;HYAL6;KIAA1199 |
NOT hyalurononglucosaminidase activity | HYAL2;HYAL3;HYAL1 |
protein binding | PCM1;C3orf62;HSPA9;TMEM123;GEMIN7;CBY1;MT1H;STAM;DIEXF |
NOT virus receptor activity | HYAL3;HYAL1 |
HYAL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HYAL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of HYAL3.
DAB1; SLC22A2
- Q&As
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