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HYAL4

  • Official Full Name

    hyaluronoglucosaminidase 4

  • Overview

    This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity.
  • Synonyms

    HYAL4; hyaluronoglucosaminidase 4; hyaluronidase-4; hyaluronidase 4; chondroitin sulfate hydrolase; CSHY; Hyal-4; HYAL4_HUMAN; Hyaluronoglucosaminidase-4;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • CHO
  • E. coli
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HYAL4-1973H Active Recombinant Human Hyaluronoglucosaminidase 4, His-tagged CHO His
Human HYAL4-14021H Recombinant Human HYAL4, GST-tagged E.coli GST 29-460a.a.
Human HYAL4-5218H Recombinant Human HYAL4 Protein, GST-tagged Wheat Germ GST
Human HYAL4-795H Recombinant Human HYAL4 protein, His-tagged E. coli His 29-460 aa
Mouse HYAL4-7955M Recombinant Mouse HYAL4 Protein Mammalian Cell His
Mouse HYAL4-4391M Recombinant Mouse HYAL4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HYAL4-4391M-B Recombinant Mouse HYAL4 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HYAL4 Related Articles
  • HYAL4 Related Research Area

HYAL4 involved in several pathways and played different roles in them. We selected most pathways HYAL4 participated on our site, such as Glycosaminoglycan degradation, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with HYAL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycosaminoglycan degradationHYAL6;HGSNAT;HYAL1;IDUA;HYAL2;GNSB;GNS;GLB1;SPAM1
Metabolic pathwaysATP6V0A1;GALNT10;PAPSS1;PNAT10;B3GNTL2;MT-ATP6;CELL;CYP19A1;SMPD3

HYAL4 has several biochemical functions, for example, hyalurononglucosaminidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HYAL4 itself. We selected most functions HYAL4 had, and list some proteins which have the same functions with HYAL4. You can find most of the proteins on our site.

Function Related Protein
hyalurononglucosaminidase activityHYAL1;HYAL6;HYAL3;HYAL2;CD44;SPAM1;HYAL4;MGEA5;KIAA1199

HYAL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HYAL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of HYAL4.

Rizzardi, AE; Vogel, RI; et al. Elevated Hyaluronan and Hyaluronan-Mediated Motility Receptor Are Associated With Biochemical Failure in Patients With Intermediate-Grade Prostate Tumors. CANCER 120:1800-1809(2014).
Shields, J; Lokeshwar, S; et al. HYAL4: A NEW HYALURONIDASE ASSOCIATED WITH BLADDER CANCER DIAGNOSIS AND PROGNOSIS. JOURNAL OF UROLOGY 191:E301-E302(2014).
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