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IFIT3

Official Full Name

interferon-induced protein with tetratricopeptide repeats 3
Overview

Interferon-induced protein with tetratricopeptide repeats 3 is a protein that in humans is encoded by the IFIT3 gene.
Synonyms

IFIT3; interferon-induced protein with tetratricopeptide repeats 3; IFIT4, interferon induced protein with tetratricopeptide repeats 4; CIG 49; GARG 49; IFI60; IRG2; ISG60; RIG G; RP11-149I23.4; CIG49; IFI-60K; IFI60K; IFIT-3; IFIT-4; IFIT3_HUMAN; IFIT4; Interferon induced 60 kDa protein; Interferon induced protein with tetratricopeptide repeats 3; Interferon-induced 60 kDa protein; Interferon-induced protein with tetratricopeptide repeats 4; ISG-60; Retinoic acid induced gene G protein; Retinoic acid-induced gene G protein; RIG-G; RIGG; CIG-49; GARG-49;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human

Source

E.coli
HEK293
HEK293T
Mammalian cells

Tag

Flag
GST
His
His (Fc)
Avi
SUMO
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	IFIT3-94H	Recombinant Human IFIT3, His-tagged	E.coli	His		Inquiry
Human	IFIT3-14069H	Recombinant Human IFIT3, GST-tagged	E.coli	GST	141-490a.a.	$319 / 25ug
Human	IFIT3-5285HCL	Recombinant Human IFIT3 293 Cell Lysate	HEK293	N/A		Inquiry
Human	IFIT3-5286HCL	Recombinant Human IFIT3 293 Cell Lysate	HEK293	N/A		Inquiry
Human	IFIT3-1145H-B	Recombinant Human IFIT3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	IFIT3-2450H	Recombinant Human IFIT3 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	IFIT3-1290HFL	Recombinant Full Length Human IFIT3 Protein, C-Flag-tagged	Mammalian cells	Flag		Inquiry
Human	IFIT3-3066H	Recombinant Human IFIT3 protein, His-SUMO-tagged	E.coli	His-SUMO	1-490aa	Inquiry
Human	IFIT3-1145H	Recombinant Human IFIT3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
IFIT3 Related Articles

IFIT3 involved in several pathways and played different roles in them. We selected most pathways IFIT3 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFIT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cytokine Signaling in Immune system	TAB1;FGF8B;SOCS3A;PRLRB;PELI1;IRF9;RASGEF1A;IFIT14;GBP5
Immune System	IFIT3;RNF216;TNFSF13B;DEFA1;EVL;DTX3L;IL1RN;DCTN6;KLRB1F
Interferon Signaling	IFIT2;TRIM3;EIF4E3;GBP1;IFIT3;SAMHD1;TRIM5;ISG20;IRF4
Interferon alpha/beta signaling	IFI27;USP18;SAMHD1;BST2;IRF2;IRF6;IRF4;XAF1;IFIT3

IFIT3 has several biochemical functions, for example, RNA binding, identical protein binding, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by IFIT3 itself. We selected most functions IFIT3 had, and list some proteins which have the same functions with IFIT3. You can find most of the proteins on our site.

Function	Related Protein
RNA binding	CTIF;RPL7;ELAVL1;PTBP2B;AGO3B;RBM39B;IFIT10;U2AF2B;NOM1
identical protein binding	PLDN;SH2B2;PTS;ADIPOQ;SH3GL3;CCT7;TGFB3;SCAND1;COL2A1
molecular_function	NDRG4;FAM149A;GPR82;MUP12;KHNYN;TMEM170B;NUP210L;GIPC2;GRXCR2
protein binding	FAM193B;JMJD7;TP53RK;H2-AB1;CATSPER1;ROBO2;HIST1H2AI;SIX4;HINFP

IFIT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFIT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFIT3.

Schmeisser, H; Mejido, J; et al. Identification of Alpha Interferon-Induced Genes Associated with Antiviral Activity in Daudi Cells and Characterization of IFIT3 as a Novel Antiviral Gene. JOURNAL OF VIROLOGY 84:10671-10680(2010).

Serrano-Fernandez, P; Moller, S; et al. Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis. AUTOIMMUNITY 43:172-178(2010).