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IGFBP1

  • Official Full Name

    Insulin-like Growth Factor Binding Protein 1

  • Overview

    This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
  • Synonyms

    AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1; IGFBP1; insulin-like growth factor-binding protein 1; IBP-1; IGFBP-1; OTTHUMP00000159561; OTTHUMP00000207990; OTTHUMP00000214348; binding protein-25; binding protein-26; binding protein-28; placental protein 12; IGF-binding protein 1; amniotic fluid binding protein; growth hormone independent-binding protein; alpha-pregnancy-associated endometrial globulin;

  • Recombinant Proteins
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Canine
  • Cattle
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Pig
  • Rat
  • Rhesus macaque
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293F
  • HEK293T
  • Human
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • Mouse Erythrocytes
  • Yeast
  • C
  • His
  • His (Fc)
  • Avi
  • His(C
  • ter)
  • His|GST
  • His|SUMO
  • His|T7
  • SUMO
  • MYC
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IGFBP1-29544TH Active Recombinant Human IGFBP1 protein E.coli N/A
Human IGFBP1-5048H Active Recombinant Human Insulin-Like Growth Factor Binding Protein 1 Human N/A
Human IGFBP1-143H Active Recombinant Human IGFBP1 Protein E.coli N/A
Human IGFBP1-821H Recombinant Human IGFBP1 protein, His & GST-tagged E.coli His/GST Asp159~Pro249 (Accession # P08833)
Human IGFBP1-39H Recombinant Human IGFBP1, His-tagged E.coli His
Human IGFBP1-79H Active Recombinant Human IGFBP1 Protein Mammalian cells N/A
Human IGFBP1-822H Recombinant Human IGFBP1 protein, His & T7-tagged E.coli His/T7 Glu36~Asn235 (Accession # P08833)
Human IGFBP1-0013H Recombinant Human IGFBP1 Protein HEK293 cells
Human IGFBP1-1387H Recombinant Human IGFBP1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human IGFBP1-612H Native Human Insulin-like Growth Factor Binding Protein 1 Mouse Erythrocytes N/A
Human IGFBP1-2488H Recombinant Human IGFBP1 Protein (Ala26-Lys162), C-His tagged E.coli C-His Ala26-Lys162
Human IGFBP1-1249H Active Recombinant Human IGFBP1 protein, His-tagged HEK293 His Ala26-Asn259
Human IGFBP1-4428H-B Recombinant Human IGFBP1 Protein Pre-coupled Magnetic Beads HEK293
Human IGFBP1-4428H Recombinant Human IGFBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IGFBP1-2490H Recombinant Human IGFBP1 Protein (Met1-Asn259), N-His tagged Mammalian cells N-His Met1-Asn259
Human IGFBP1-2489H Recombinant Human IGFBP1 Protein (Ala26-Asn259), C-His tagged E.coli C-His Ala26-Asn259
Human IGFBP1-131H Recombinant Human IGFBP1 Protein, His-tagged(C-ter) HEK293 His(C-ter) Ala26-Asn259
Human IGFBP1-2491H Recombinant Human IGFBP1 Protein (Ala26-Asn259), N-His tagged E.coli N-His Ala26-Asn259
Human IGFBP1-03H Active Recombinant Human IGFBP-1 Protein (26-259aa) HEK293 26-259aa
Human IGFBP1-4259H Recombinant Human IGFBP1 Protein (Met1-Asn259), C-His tagged Mammalian cells C-His Met1-Asn259
Mouse Igfbp1-5643M Active Recombinant Mouse Insulin-Like Growth Factor Binding Protein 1 Mammalian cells N/A
Mouse IGFBP1-8071M Recombinant Mouse IGFBP1 Protein Mammalian Cell His
Mouse Igfbp1-1226M Recombinant Mouse Igfbp1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse IGFBP1-4467M-B Recombinant Mouse IGFBP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Igfbp1-3082M Recombinant Mouse Igfbp1 protein, His-SUMO-tagged E.coli His-SUMO 26-272aa
Mouse IGFBP1-574M Recombinant Mouse IGFBP1 Protein (26-272 aa), His-SUMO-tagged E.coli His/SUMO 26-272 aa
Mouse Igfbp1-5435M Recombinant Mouse Igfbp1 protein, His-tagged Yeast His 26-272aa
Mouse IGFBP1-4467M Recombinant Mouse IGFBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Igfbp1-10568M Recombinant Mouse Igfbp1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Igfbp1-10568M-B Recombinant Mouse Igfbp1 Protein Pre-coupled Magnetic Beads HEK293
Rat Igfbp1-31R Recombinant Rat Igfbp1 protein, His-tagged E.coli His Met1~Asn272
Rat IGFBP1-3007R Recombinant Rat IGFBP1 Protein Mammalian Cell His
Rat Igfbp1-3083R Recombinant Rat Igfbp1 protein, His-tagged E.coli His 26-272aa
Rat IGFBP1-2663R-B Recombinant Rat IGFBP1 Protein Pre-coupled Magnetic Beads HEK293
Rat Igfbp1-3084R Recombinant Rat Igfbp1 protein, His-SUMO-tagged E.coli His-SUMO 26-272aa
Rat Igfbp1-3085R Recombinant Rat Igfbp1 protein E.coli N/A 26-272aa
Rat Igfbp1-988R Recombinant Rat Igfbp1 Protein, His-tagged HEK293F N-His Ala26-Asn272
Rat IGFBP1-2663R Recombinant Rat IGFBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Canine IGFBP1-1065C Recombinant Canine IGFBP1 Protein, His-tagged HEK293 His
Cattle IGFBP1-820C Recombinant Cattle IGFBP1 protein, His & T7-tagged E.coli His/T7 Asp112~Asn263 (Accession # P24591)
Cynomolgus Monkey IGFBP1-1482CCL Recombinant Cynomolgus IGFBP1 cell lysate Human Cell N/A
Rhesus Macaque IGFBP1-1189R Active Recombinant Rhesus IGFBP1 Protein, His-tagged HEK293 His
Rhesus macaque IGFBP1-300R Recombinant Rhesus macaque IGFBP1 Protein, His-tagged HEK293 His 281
Rhesus macaque IGFBP1-822R Recombinant Rhesus macaque IGFBP1 protein, His-tagged HEK293 His Ala48-Asn281
Pig IGFBP1-823P Recombinant Pig IGFBP1 protein, His & T7-tagged E.coli His/T7 Glu112~Asn262 (Accession # Q75ZP3)
Chicken IGFBP1-1081C Recombinant Chicken IGFBP1 Mammalian Cell His
  • IGFBP1 Related Articles
  • IGFBP1 Related Research Area

IGFBP1 involved in several pathways and played different roles in them. We selected most pathways IGFBP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IGFBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

IGFBP1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by IGFBP1 itself. We selected most functions IGFBP1 had, and list some proteins which have the same functions with IGFBP1. You can find most of the proteins on our site.

Function Related Protein

IGFBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGFBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGFBP1.

Otti, GR; Saleh, L; et al. Notch2 Controls Prolactin and Insulin-Like Growth Factor Binding Protein-1 Expression in Decidualizing Human Stromal Cells of Early Pregnancy. PLOS ONE 9:-(2014).
Park, SJ; Sawitzki, B; et al. Serum biomarkers for neurofibromatosis type 1 and early detection of malignant peripheral nerve-sheath tumors. BMC MEDICINE 11:-(2013).
  • Q&As
  • Reviews

Q&As (7)

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How does IGFBP1 contribute to the development and progression of cancers, especially hormone-dependent cancers? 05/02/2022

IGFBP1 influences the progression of certain cancers, particularly those sensitive to hormonal regulation.

How do changes in IGFBP1 expression affect aging and age-related diseases? 12/17/2021

Changes in IGFBP1 expression contribute to the aging process and the development of age-related diseases.

What is the impact of IGFBP1 on fetal growth and development during pregnancy? 12/19/2020

IGFBP1 is important for fetal growth and development, regulating growth factor activity during pregnancy.

How does IGFBP1 influence muscle growth and regeneration, particularly in muscle-wasting conditions? 01/10/2020

IGFBP1 affects muscle growth and regeneration, playing a role in conditions involving muscle wasting.

What are the effects of IGFBP1 on cardiovascular health and diseases such as atherosclerosis? 08/09/2019

IGFBP1 impacts cardiovascular health, influencing factors like blood vessel growth and atherosclerosis development.

What role does IGFBP1 play in metabolic processes, particularly in glucose homeostasis and insulin sensitivity? 01/20/2018

IGFBP1 plays a crucial role in glucose metabolism and insulin sensitivity, impacting overall metabolic health.

How does IGFBP1 regulate the activity of insulin-like growth factors (IGFs) in different tissues? 01/15/2018

IGFBP1 modulates the availability and activity of IGFs, affecting growth and metabolic functions in various tissues.

Customer Reviews (3)

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Reviews
06/13/2022

    Precise antibody validation, enhances immunoprecipitation studies.

    03/12/2019

      Efficient protein purification, delivers high yield and purity.

      06/25/2018

        Dependable expertise in protein engineering, unmatched quality.

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