il12rb2
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  • Official Full Name
  • interleukin 12 receptor, beta 2
  • Background
  • The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohns disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
  • Synonyms
  • IL12RB2; interleukin 12 receptor, beta 2; interleukin-12 receptor subunit beta-2; I12R2_HUMAN; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; IL-12R-beta-2; IL-12RB2; IL12 receptor beta 2; IL12R beta2; Interleukin 12 receptor beta 2; Interleukin 12 receptor beta 2 chain; RP11 102M16.1; IL-12 receptor beta 2; interleukin-12 receptor beta-2 chain; RP11-102M16.1
Cat.#:IL12RB2-1464HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL12RB2 protein, His-tagged
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Cat.#:IL12RB2-1465HTag:His & GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL12RB2 protein, His & GST-tagged
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Cat.#:IL12RB2-29640THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human IL12RB2
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Cat.#:IL12RB2-3884HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human IL12RB2 protein, His-tagged
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Cat.#:Il12rb2-1466MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il12rb2 protein, His-tagged
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Cat.#:Il12rb2-1467MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il12rb2 protein, His-tagged
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Cat.#:Il12rb2-4006MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Il12rb2, His tagged
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Cat.#:IL12RB2-5006CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken IL12RB2
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Cat.#:IL12RB2-6304ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish IL12RB2
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Cat.#:IL12RB2-2142MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse IL12RB2 cell lysate
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Il12rb2 Related Articles

Holle, JU; Gross, WL; et al. Genetic risk factors for vasculitis. INTERNIST 55:128-+(2014).
Cho, S; Kim, J; et al. Immunopathogenic characterization of cutaneous inflammation in Behcet's disease. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 28:51-57(2014).

Il12rb2 Related Gene Family

IL