IL23
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Marmoset
- Mouse
- CHO
- HEK293
- Human Cell
- Insect Cell
- C
- His
- Fc
- Fc|His
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- IL23 Related Gene Family
IL23 involved in several pathways and played different roles in them. We selected most pathways IL23 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Pertussis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | TNFRSF10C;IFNA5;Ccl9;BMP7A;CRFB4;IFNL3;TNFB;CXCL9;CCR5 |
| Jak-STAT signaling pathway | IL10RA;BCL2L1;AOX3;IL2RG;PIK3CB;SOCS7;CSF3;CSH;CCND2 |
| Pertussis | CASP7;CALM4;ITGAM;C3;MAPK12;GNAI2;PYCARD;CFL2;NLRP3 |
| Tuberculosis | SPHK2;HLA-DQA1;HLA-DQA2;ATP6V0A2;MAPK9;MRC2;CAMK2A;IL23;MRC1 |
| Inflammatory bowel disease (IBD) | SMAD2;IL6;IL21R;HLA-DRB4;H2-AB1;IL12RB1;HLA-DOA;RORA;STAT3 |
| Rheumatoid arthritis | IFNG;TNFRSF11A;CCL20;ATP6V1C1;TGFB2;ATP6V1A;HLA-DQA2;HLA-DRB5;IL15 |
IL23 has several biochemical functions, for example, cytokine activity, contributes_to interleukin-23 receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL23 itself. We selected most functions IL23 had, and list some proteins which have the same functions with IL23. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | CMTM1;TNFSF12;CSF1B;GM13285;WNT1;TNFSF13;CD70;IFNB1;GDF10 |
| contributes_to interleukin-23 receptor binding | IL12B;IL23;Il23a; Il12b |
| protein binding | TRPC1;RSU1;ZNF124;CCDC24;EVI5L;MYPOP;TNNC2;MYH7B;SLC3A2 |
IL23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL23 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL23.
IL12B; PEX19; IL12RB1
- Q&As
- Reviews
Q&As (10)
Ask a questionIL23 expression correlates with disease severity in psoriasis.
IL23 expression varies among dendritic cells and macrophages.
IL23 activates STAT3 to modulate downstream targets.
IL23 interacts with IL-12 to form a signaling cascade.
IL23 is involved in the activation of STAT3.
IL23 expression is upregulated in autoimmune diseases like Crohn's.
The half-life of IL23 in plasma is approximately 2 hours.
IL23 induces M1 macrophage polarization.
IL23 promotes Th17 cell differentiation by activating STAT3.
IL23 contributes to tissue inflammation by activating macrophages.
Customer Reviews (3)
Write a reviewHigh purity levels in CHIP
Effective in T-cell differentiation.
Suitable for signaling studies.
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