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ILF2

  • Official Full Name

    interleukin enhancer binding factor 2, 45kDa

  • Overview

    Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of this gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression.
  • Synonyms

    ILF2; interleukin enhancer binding factor 2, 45kDa; interleukin enhancer binding factor 2, 45kD; interleukin enhancer-binding factor 2; NF45; nuclear factor of activated T-cells 45 kDa; nuclear factor of activated T-cells, 45-kDa; PRO3063; MGC8391;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ILF2-29033TH Recombinant Human ILF2, His-tagged E.coli His
Human ILF2-5222HCL Recombinant Human ILF2 293 Cell Lysate HEK293 N/A
Human ILF2-5137H Recombinant Human ILF2 protein, GST-tagged E.coli GST 1-390aa
Human ILF2-5717HF Recombinant Full Length Human ILF2 Protein, GST-tagged In Vitro Cell Free System GST 390 amino acids
Human ILF2-5162H Recombinant Human ILF2 Protein, GST-tagged Wheat Germ GST
Human ILF2-1181H Recombinant Human ILF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ILF2-2050HFL Recombinant Full Length Human ILF2 Protein, C-Flag-tagged Mammalian cells Flag
Human ILF2-1181H-B Recombinant Human ILF2 Protein Pre-coupled Magnetic Beads HEK293
Mouse ILF2-8185M Recombinant Mouse ILF2 Protein Mammalian Cell His
Mouse Ilf2-3524M Recombinant Mouse Ilf2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse ILF2-4523M-B Recombinant Mouse ILF2 Protein Pre-coupled Magnetic Beads HEK293
Mouse ILF2-4523M Recombinant Mouse ILF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ILF2-3050R Recombinant Rat ILF2 Protein Mammalian Cell His
Rat ILF2-2706R Recombinant Rat ILF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ILF2-2706R-B Recombinant Rat ILF2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ILF2-2258R Recombinant Rhesus monkey ILF2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ILF2-2079R Recombinant Rhesus Macaque ILF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ILF2-2079R-B Recombinant Rhesus Macaque ILF2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish ILF2-12438Z Recombinant Zebrafish ILF2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ILF2 Related Articles

ILF2 involved in several pathways and played different roles in them. We selected most pathways ILF2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ILF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ILF2 has several biochemical functions, for example, ATP binding, DNA binding, double-stranded RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ILF2 itself. We selected most functions ILF2 had, and list some proteins which have the same functions with ILF2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingATP1A4;DHX33;LANCL2;PRKACA;SMYHC1;CSK;DGUOK;IGF1RB;ATAD5B
DNA bindingZNF238;ZSCAN2;TOPORS;SOX19A;SSRP1A;CASZ1;FOXS1;POLR3H;APITD1
double-stranded RNA bindingTFRC;RFTN1;MBNL1;STRBP;ILF2;MYH4;OASL1;MTDH;OASL
poly(A) RNA bindingKIAA1429;ALDH18A1;GTF2E2;D19BWG1357E;RPL10;RPS21;MKRN1;LSM8;RPS2
protein bindingSPINK7;DRAP1;ABI3;MYL6B;ZSCAN1;CEACAM21;ACACA;LBR;SSBP1
transferase activityUGT1A2;B3GNT2B;SUV39H1A;cka1;ST3GAL3A;DNAJC3B;HYKK.2;TRIO;GSTM

ILF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ILF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ILF2.

YBX1; ILF3; PPID; VCAM1

Marchesini, M; Storti, P; et al. ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma. BLOOD 124:-(2014).
Cardenas, G; Fragoso, G; et al. Neurocysticercosis: the effectiveness of the cysticidal treatment could be influenced by the host immunity. MEDICAL MICROBIOLOGY AND IMMUNOLOGY 203:373-381(2014).
  • Q&As
  • Reviews

Q&As (5)

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What are the potential applications of ILF2 in tumor immunotherapy? 09/19/2019

As an immunomodulatory factor, ILF2 has a potential application prospect in tumor immunotherapy, but its specific role and application value still need to be further studied and clinical trials.

Do the regulators of the ILF2 signaling pathway interact with other protein mushrooms? 08/16/2019

The regulation of ILF2 signaling pathway may involve other transcription factors, cytokines, protein kinases and other factors, including IRF4, STAT1, NF-κB and so on.

Does the structure-function relationship of ILF2 have to do with it? 06/18/2019

ILF2 the relationship between structure and function has not been fully elucidated, by studying aspects such as its domain structure, protein interactions can be insight into its function mechanism.

In the existing studies, what are the main biological functions of ILF2? 04/30/2019

ILF2 is involved in cell proliferation, apoptosis, inflammatory response, antiviral immunity and other biological processes, but its specific function and mechanism still need to be further studied.

What diseases or pathological processes are ILF2 associated with? 03/23/2019

This protein is related to some inflammatory diseases, tumors and immune regulation, such as liver cancer, breast cancer, rheumatoid arthritis and so on.

Customer Reviews (3)

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Reviews
11/12/2021

    No adverse reactions, small side effects.

    01/19/2021

      The safety is very high, and no side effects are found after long-term use.

      12/02/2020

        Easy to operate, easy to use, will recommend to others.

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