ILF2
-
Official Full Name
interleukin enhancer binding factor 2, 45kDa
-
Overview
Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of this gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression. -
Synonyms
ILF2; interleukin enhancer binding factor 2, 45kDa; interleukin enhancer binding factor 2, 45kD; interleukin enhancer-binding factor 2; NF45; nuclear factor of activated T-cells 45 kDa; nuclear factor of activated T-cells, 45-kDa; PRO3063; MGC8391;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- ILF2 Related Articles
ILF2 involved in several pathways and played different roles in them. We selected most pathways ILF2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ILF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|
ILF2 has several biochemical functions, for example, ATP binding, DNA binding, double-stranded RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ILF2 itself. We selected most functions ILF2 had, and list some proteins which have the same functions with ILF2. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
ATP binding | ATP1A4;DHX33;LANCL2;PRKACA;SMYHC1;CSK;DGUOK;IGF1RB;ATAD5B |
DNA binding | ZNF238;ZSCAN2;TOPORS;SOX19A;SSRP1A;CASZ1;FOXS1;POLR3H;APITD1 |
double-stranded RNA binding | TFRC;RFTN1;MBNL1;STRBP;ILF2;MYH4;OASL1;MTDH;OASL |
poly(A) RNA binding | KIAA1429;ALDH18A1;GTF2E2;D19BWG1357E;RPL10;RPS21;MKRN1;LSM8;RPS2 |
protein binding | SPINK7;DRAP1;ABI3;MYL6B;ZSCAN1;CEACAM21;ACACA;LBR;SSBP1 |
transferase activity | UGT1A2;B3GNT2B;SUV39H1A;cka1;ST3GAL3A;DNAJC3B;HYKK.2;TRIO;GSTM |
ILF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ILF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ILF2.
YBX1; ILF3; PPID; VCAM1
- Q&As
- Reviews
Q&As (5)
Ask a questionAs an immunomodulatory factor, ILF2 has a potential application prospect in tumor immunotherapy, but its specific role and application value still need to be further studied and clinical trials.
The regulation of ILF2 signaling pathway may involve other transcription factors, cytokines, protein kinases and other factors, including IRF4, STAT1, NF-κB and so on.
ILF2 the relationship between structure and function has not been fully elucidated, by studying aspects such as its domain structure, protein interactions can be insight into its function mechanism.
ILF2 is involved in cell proliferation, apoptosis, inflammatory response, antiviral immunity and other biological processes, but its specific function and mechanism still need to be further studied.
This protein is related to some inflammatory diseases, tumors and immune regulation, such as liver cancer, breast cancer, rheumatoid arthritis and so on.
Customer Reviews (3)
Write a reviewNo adverse reactions, small side effects.
The safety is very high, and no side effects are found after long-term use.
Easy to operate, easy to use, will recommend to others.
Ask a Question for All ILF2 Products
Required fields are marked with *
My Review for All ILF2 Products
Required fields are marked with *