IMP4
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Official Full Name
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
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Overview
IMP4 forms a ternary complex with IMP3 (MIM 612980) and MPP10 (MPHOSPHO10; MIM 605503) that interacts with U3 small;nucleolar RNA (snoRNA), which is required for the early cleavage steps in pre-rRNA processing (Granneman et al., 2003;(PubMed 12655004)). -
Synonyms
IMP4; IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast); U3 small nucleolar ribonucleoprotein protein IMP4; BXDC4; MGC19606; D1Wsu40e; U3 snoRNP protein 4 homolog; U3 snoRNP protein IMP4; Brix domain containing protein 4; Brix domain-containing protein 4; IMP4_HUMAN; LRRGT00017;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- IMP4 Related Articles
IMP4 involved in several pathways and played different roles in them. We selected most pathways IMP4 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with IMP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome biogenesis in eukaryotes | GNL2;RCL1;NOP10;UTP18;NHP2L1;NAT10;BMS1;NXT1;MPHOSPH10 |
IMP4 has several biochemical functions, for example, protein binding, rRNA primary transcript binding, snoRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IMP4 itself. We selected most functions IMP4 had, and list some proteins which have the same functions with IMP4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PPP2R3A;ZBTB48;TXNDC12;SYCP1;CEP63;SESN2;MYCBP2;TRIM69;ZC3H10 |
| rRNA primary transcript binding | NCL;RPF1;IMP4;PTRF |
| snoRNA binding | UTP15;TBL3;NOP56;NUDT16L1;HEATR1;PWP2;WDR3;IMP4;NUDT4 |
IMP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IMP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of IMP4.
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- Q&As
- Reviews
Q&As (6)
Ask a questionIMP4 plays an important role in cardiovascular diseases and can regulate processes such as vascular endothelial cell function, angiogenesis, and myocardial protection.
It can regulate the expression of insulin receptor and glucose metabolism regulation genes, and affect the insulin signaling pathway and glucose metabolism regulation and other physiological processes.
It can adjust process, the differentiation of hematopoietic stem cells and blood cells and blood system diseases such as leukemia associated with anemia, etc.
IMP4 has been used in the treatment of cancer, cardiovascular diseases, metabolic diseases, and as a potential target for stem cell therapy and gene therapy.
Play an important role in liver cancer, can regulate liver cancer stem cells and tumor angiogenesis process, and promote the occurrence and development of liver cancer.
This protein can regulate the expression of a variety of genes, affect the proliferation, migration, transformation and EMT process of tumor cells, and participate in the occurrence and development of tumors.
Customer Reviews (3)
Write a reviewThe cost is moderate, the performance is good, and the experiment is more cost-effective.
Easy to adhere to the surface of the material, reduce the loss of reagents, reduce costs.
IMP4 is environmentally friendly and does little harm to the human body.
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