INCA1
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Official Full Name
inhibitor of CDK, cyclin A1 interacting protein 1
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Synonyms
INCA1; inhibitor of CDK, cyclin A1 interacting protein 1; protein INCA1; HSD45; MGC148150; MGC148151;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | INCA1-345HCL | Recombinant Human INCA1 lysate | HEK293 | N/A |
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| Mouse | INCA1-8204M | Recombinant Mouse INCA1 Protein | Mammalian Cell | His |
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| Mouse | INCA1-4540M | Recombinant Mouse INCA1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | INCA1-4540M-B | Recombinant Mouse INCA1 Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
- INCA1 Related Articles
INCA1 involved in several pathways and played different roles in them. We selected most pathways INCA1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with INCA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
INCA1 has several biochemical functions, for example, cyclin binding, cyclin-dependent protein serine/threonine kinase inhibitor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INCA1 itself. We selected most functions INCA1 had, and list some proteins which have the same functions with INCA1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cyclin binding | PFTK1;FBXW7;CDK12;CDK14;CDK13;CDK5RAP3;CDK6;CDKN1A;INCA1 |
| cyclin-dependent protein serine/threonine kinase inhibitor activity | CDKN2A;CDKN1D;CDKN2D;CDKN2C;CDKN1A;CDKN1BB;HEXIM2;KAT2B;CDKN1C |
| protein binding | SOX10;ZNF274;NSL1;DEDD2;SRGN;DHRS1;LDOC1;PTPN22;C17orf62 |
INCA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INCA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of INCA1.
SAP18; EPHB6; STK16; COL8A1; CDKN2D; GRB2
- Q&As
- Reviews
Q&As (6)
Ask a questionThe proteins associated with inflammatory bowel disease, autoimmune disease, such as, such as arthritis, inflammatory bowel disease.
The research on tumor is relatively preliminary, but there is evidence that INCA1 plays an inhibitory role in some tumors and is involved in the regulation of tumor cell proliferation and metastasis.
Yes, INCA1 plays an important role in the regulation of immune response by inhibiting the nuclear factor κB signaling pathway to regulate the activation of immune cells and inflammatory response.
No report on the resolution of the structure of INCA1 protein has been found so far, and further studies may be needed to reveal its structure and function.
It is involved in the development and regulation of inflammatory bowel disease, and may affect the progression of the disease by regulating the production of inflammatory factors and the activation of immune cells.
Studies have shown that INCA1 is involved in the regulation of antioxidant response and alleviates oxidative stress damage by inhibiting the activity of nuclear factor-κb kinase.
Customer Reviews (3)
Write a reviewKinetic parameters such as enzymatic reaction rate and binding affinity were tested in the early stage, and it was found that the protein performed well.
Will not interact with other reagents, will not affect.
Good stability under different temperature and humidity conditions.
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