ING4
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Official Full Name
inhibitor of growth family, member 4
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Overview
This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. -
Synonyms
ING4; inhibitor of growth family, member 4; inhibitor of growth protein 4; my036; p29ING4; brain my036 protein; candidate tumor suppressor p33 ING1 homolog; MGC12557;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Zebrafish
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Fc|His
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- ING4 Related Articles
ING4 involved in several pathways and played different roles in them. We selected most pathways ING4 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with ING4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Chromatin modifying enzymes | KANSL3;SUZ12A;MBD3B;EHMT2;YEATS4;TADA1;TADA3;SAP30L;MSL2A |
Chromatin organization | KDM5A;BRPF3;KDM4B;GATAD2AB;SAP30L;DPY30;PRMT7;DR1;DNMT3A |
HATs acetylate histones | EPC1;EP400;TADA2A;C3orf75;ATXN7L3;JADE1;RBB4L;PAX3A;ELP2 |
ING4 has several biochemical functions, for example, methylated histone binding, protein binding, transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ING4 itself. We selected most functions ING4 had, and list some proteins which have the same functions with ING4. You can find most of the proteins on our site.
Function | Related Protein |
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methylated histone binding | CHD8;CBX5;WDR92;MTF2;MSL3;CDYL2;SUZ12;CCDC101;ING1 |
protein binding | PRKAA1;MRPL20;BATF2;HEYL;ELP4;SEMG2;PFN2;CCND2;NSG1 |
transcription coactivator activity | POU2AF1;KLF7;WWC1;TFAP2A;NR5A1;TADA2A;SUB1A;PQBP1;PARK7 |
zinc ion binding | ZCCHC9;APOBEC2B;PAPLNB;ADAM15;MEP1A;BTR12;ADAM9;ZNF638;CAR6 |
ING4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ING4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ING4.
HNRNPD; NAV2; HIST1H3D; HNRNPD; HNRNPD; HNRNPD; HNRNPD
- Q&As
- Reviews
Q&As (7)
Ask a questionThe molecular weight of ING4 is approximately 36 kDa.
ING4 is mainly found in the nucleus of cells.
The ING4 protein is encoded by the ING4 gene.
Yes, mutations in the ING4 gene have been associated with certain cancers.
ING4 is involved in regulating cell growth, apoptosis, and DNA repair.
ING4 stands for “Inhibitor of Growth 4
Yes, ING4 is considered a tumor suppressor and its loss of function can contribute to cancer development.
Customer Reviews (3)
Write a reviewComprehensive documentation streamlined the integration of the product into our experimental workflow.
Replicating results underscored the reliability and relevance of the product's effects.
Minimal background noise in our assays was indicative of the product's superior quality.
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