INMT
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Official Full Name
indolethylamine N-methyltransferase
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Overview
N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream FAM188B (family with sequence similarity 188, member B) gene. -
Synonyms
INMT; indolethylamine N-methyltransferase; Amine N methyltransferase; Amine N-methyltransferase; Aromatic alkylamine N methyltransferase; Aromatic alkylamine N-methyltransferase; Arylamine N methyltransferase; Arylamine N-methyltransferase; Indolamine N-methyltransferase; Indolethylamine N methyltransferase; INMT_HUMAN; nicotine N methyltransferase; thioester S methyltransferase like; nicotine N-methyltransferase;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rabbit
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- His|SUMO
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- INMT Related Articles
INMT involved in several pathways and played different roles in them. We selected most pathways INMT participated on our site, such as Selenocompound metabolism, Tryptophan metabolism, nicotine degradation IV, which may be useful for your reference. Also, other proteins which involved in the same pathway with INMT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Selenocompound metabolism | MTR;CCBL2;TRR1;TXNRD3;TXNRD1;SEPSECS;TXNRD2;PSTK;SPS2 |
Tryptophan metabolism | OGDH;TPH1;CCBL2;CYP1A;CYP4F12;AOX2P;TDO2;CMTM2A;ACAT1 |
nicotine degradation IV |
INMT has several biochemical functions, for example, amine N-methyltransferase activity, protein binding, thioether S-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INMT itself. We selected most functions INMT had, and list some proteins which have the same functions with INMT. You can find most of the proteins on our site.
Function | Related Protein |
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amine N-methyltransferase activity | |
protein binding | MED10;EDNRA;MEAF6;SSX2;CD36;SPATC1;SNX17;USP19;RNF6 |
thioether S-methyltransferase activity |
INMT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INMT here. Most of them are supplied by our site. Hope this information will be useful for your research of INMT.
KLHL12
- Q&As
- Reviews
Q&As (7)
Ask a questionINMT is classified as a methyltransferase and functions as a transferase enzyme.
This reaction has relevance in various biochemical and physiological processes.
INMT catalyzes the N-methylation of tryptamine and structurally related compounds.
It functions as a thioether S-methyltransferase, acting on various thioethers and related selenium and tellurium compounds.
Indolethylamine N-methyltransferase.
INMT is involved in the detoxification of selenium compounds.
INMT is active with compounds like 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide, and diethyl sulfide.
Customer Reviews (3)
Write a reviewThe product's customizability allowed us to fine-tune experiments to match our specific research objectives.
The product's versatility allowed us to apply it to a wide range of experimental techniques and research areas.
We appreciated the product's efforts to minimize its environmental footprint through sustainable manufacturing practices.
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